Publications by authors named "S S Olesen"
Background: Abdominal pain is the cardinal symptom of acute pancreatitis (AP), often requiring opioid therapy. This study aimed to investigate the dose-dependent relationship between opioid therapy and moderately severe or severe AP.
Methods: This was a post-hoc analysis of the prospective PAINAP database, which recruited patients with first-time AP from 118 centres across 27 countries between April-June 30, 2022.
Objectives: Activation of type M2 macrophages has been implicated in the pathogenesis of chronic pancreatitis (CP). In a clinical pilot study, we investigated blood-based markers of macrophage activation at different stages of CP.
Methods: We performed a cross-sectional analysis of prospectively collected plasma samples from healthy controls and patients with suspected or definitive CP according to the M-ANNHEIM criteria.
Purpose: Routinely collected clinical data are a valuable resource for epidemiological research in infectious diseases. We examined the validity of the ICD-10 diagnosis code K75.0 for pyogenic liver abscess (PLA) from hospital discharge registries.
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- The study investigates pancreatic atrophy in patients with chronic pancreatitis (CP) to establish diagnostic standards and analyze factors affecting the condition.
- Measurements of pancreatic size and associated variables like calcifications were collected from a cohort of 539 CP patients to determine cutoffs for identifying atrophy and its link to exocrine pancreatic dysfunction (EPD).
- Results show that specific pancreatic size measurements are linked to EPD, with male sex, older age, and longer CP duration being significant risk factors for pancreatic atrophy.