Acute metabolic decompensation after liver transplant in a patient with maple syrup urine disease.

Maple syrup urine disease (MSUD) is an inborn error of metabolism characterized by the accumulation of branched-chain amino acids (leucine, isoleucine, and valine) caused by a defect in the branched-chain alpha-keto acid dehydrogenase complex. Liver transplant is an effective therapy for MSUD, and patients can usually tolerate a regular diet after transplant without symptomatic metabolic decompensation. Most post-transplant patients do not follow a sick-day diet.

Exposing a Motherhood Penalty in Sport: A Feminist Narrative Inquiry of Media Stories of Canadian Athlete Mothers' Journeys to the 2020 Tokyo Games.

Coinciding with athlete mothers' stories gaining media visibility, sport media researchers are studying media discourses to learn more about socially constructed motherhood and sport. The present study extends media research on elite athlete mothers, by using feminist narrative inquiry to interrogate discrimination meanings in sport. North American sport media stories were collected on Canadian athletes' (i.

Off-the-shelf implant to bridge a urethral defect: multicentre 8-year journey from bench to bed.

Objective: To engineer an acellular mesh to reconstruct the urethra to replace the current surgical practice of using autologous tissue grafts. Cell based approaches have shown progress. However, these have been associated with high costs and logistical challenges.

Impact of Virtual Clinics on Streamlining NHS Outpatient Waiting Lists and Carbon Emissions.

Background: The National Health Service (NHS) outpatient waiting list is growing, affecting specialties like foot and ankle. Delays are due to increasing demand, limited resources, and administrative inefficiencies. Virtual clinics are being explored to reduce physical clinic burdens and provide timely care.

A chromosome-level genome of the giant vinegaroon Mastigoproctus giganteus exhibits the signature of pre-Silurian whole genome duplication.

Within the arachnids, chromosome-level genome assemblies have greatly accelerated the understanding of gene family evolution and developmental genomics in key groups, such as spiders (Araneae), mites and ticks (Acariformes and Parasitiformes). Among other poorly studied arachnid orders that lack genome assemblies altogether are the clade Pedipalpi, which is comprised of three orders that form the sister group of spiders, which diverged over 400 Mya. We close this gap by generating the first chromosome-level assembly from a single specimen of the vinegaroon Mastigoproctus giganteus (Uropygi).