Myasthenia Gravis as a Paraneoplastic Manifestation of Renal Cell Carcinoma: More Than a Coincidence?

Background: Myasthenia gravis is an autoimmune neuromuscular disease primarily caused by autoantibodies against nicotinic acetylcholine receptors (AChRs) at the neuromuscular junction. However, extrathymic malignancies need to be considered in the elderly population.

Purpose: Although thymic malignancy is the most common tumour association, several extrathymic malignancies complicated with myasthenia gravis have been reported.

Inclisiran as a siRNA Inhibitor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9); Past, Present, and Future.

Reducing low-density lipoprotein cholesterol (LDL-C) levels has been shown to reduce the risk of developing atherosclerotic cardiovascular disease (ASCVD). Statins are the foundation of LDL-C lowering therapy with other non-statin agents used in circumstances where goal LDL-C levels are not reached or owing to intolerance to adverse effects of statins. In 2003, the discovery of the role of the proprotein convertase subtilisin/kexin type 9 (PCSK9) system in promoting elevated LDL-C levels led to new avenues of drug development to achieve target LDL-C.

Iatrogenic Cardiac Arrest During Thyroid Storm.

Introduction: Thyroid storm is a life-threatening condition with often severe cardiac implications. Correct treatment choices can vary depending on underlying cardiac systolic function.

Case Description: We present a case of a 47-year-old male with untreated Grave's disease who presented with a thyroid storm.

Fabrication of binder-less metal electrodes for electrochemical water splitting - A review.

The escalating demand for green hydrogen (H) as a sustainable energy carrier has attracted intensive research into efficient water electrolysis methods. Promising candidates have emerged as binder-less metal electrodes, which enhance electrochemical performance and durability by reducing electron hindrance and avoiding binder degradation. Despite their potential, a comprehensive understanding of various binder-less fabrication techniques remains limited in the existing literature.