EXERIENCE IN PREVENTING THE CONSEQUENCES OF MALARIA IMPORTATION IN THE METROPOLIS OF MOSCOW, RUSSIA.

The main purpose of the epidemiological surveillance system for malaria in the Russian Federation is now to prevent the possible consequences of malaria-imported by Russians and foreigners from endemic areas. A quarter of the approximately 100 cases notified each year in the country are detected in Moscow. During an epidemic season, a package of measures to identify infection sources (malaria patients and parasite carriers) and to decline the number of malaria vectors is implemented and the sanitary state, of open water bodies and the efficiency of larvicidal measures are supervised.

Immunostimulating complexes incorporating Eimeria tenella antigens and plant saponins as effective delivery system for coccidia vaccine immunization.

Immunostimulating complexes (ISCOMs) are unique, multimolecular structures formed by encapsulating antigens, lipids, and triterpene saponins of plant origin, and are an effective delivery system for various kinds of antigens. The uses of ISCOMs formulated with saponins from plants collected in Kazakhstan, with antigens from the poultry coccidian parasite Eimeria tenella, were evaluated for their potential use in developing a vaccine for control of avian coccidiosis. Saponins isolated from the plants Aesculus hippocastanum and Glycyrrhiza glabra were partially purified by HPLC.

Molecular characterization of virulent Newcastle disease virus isolates from chickens during the 1998 NDV outbreak in Kazakhstan.

Newcastle disease virus (NDV) infects domesticated and wild birds throughout the world and has the possibility to cause outbreaks in chicken flocks in future. To assess the evolutionary characteristics of 10 NDV strains isolated from chickens in Kazakhstan during 1998 we investigated the phylogenetic relationships among these viruses and viruses described previously. For genotyping, fusion (F) gene phylogenetic analysis (nucleotide number 47-421) was performed using sequences of Kazakhstanian isolates as compared to sequences of selected NDV strains from GenBank.