Publications by authors named "S S Kahraman"
Importance: Clinical trials are vital for advancing cancer treatments and improving patient outcomes. Understanding the factors that influence participants' decision-making is critical for enhancing trial recruitment.
Objective: To evaluate the attitudes of patients with cancer and their relatives toward clinical trial participation, identifying key barriers and motivators that affect their willingness to engage in such trials.
: Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, but their use is associated with a spectrum of immune-related adverse events (irAEs), including endocrine disorders. This study aims to investigate the incidence, timing, treatment modalities, and impact of ICI-related endocrine side effects in cancer patients. : This retrospective study analyzed 139 cancer patients treated with ICIs between 2016 and 2022.
View Article and Find Full Text PDF: As colorectal cancers are histopathologically and molecularly highly heterogeneous tumors, it is necessary to consider the tumor's microenvironment as well as its cellular characteristics in order to determine the biological behavior of the tumor. This study included 100 patients who underwent resection for colorectal cancer. We aimed to investigate the relationships between the expression status of the HIF-1α, LOX and ITGA5 proteins and clinicopathologic parameters.
View Article and Find Full Text PDFThis study explores the role of mindfulness in marriage as a potential mediator in the relationship between infidelity tendencies and divorce anxiety among married individuals. Employing a sample of 415 married individuals, the research utilized a correlational model to examine the predictive capacity of marital mindfulness. The assessment involved the Mindfulness in Marriage Scale, Infidelity Tendency Scale, and Divorce Anxiety Scale, supplemented by a demographic information form.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to compare the detection rates of breast cancer-related lymphedema (BCRL) using two methods: perometer and circumferential measurements, in patients who had breast cancer surgery.
- A total of 101 female patients were monitored over 12 months, revealing that 34.7% showed signs of subclinical BCRL using circumferential measures, while 23.8% did so via perometer, with no significant difference in quality of life or functionality between those with and without subclinical lymphedema.
- The researchers recommend regular monitoring for BCRL by the same healthcare provider and educating patients to enable early detection and intervention.