[Autopsy study in the analysis of cardiovascular mortality].

The frequency of using autopsy to verify the cardiovascular causes of death was studied in typical regions of Russia. One thousand and sixty deaths from circulatory system diseases were analyzed among a representative sample of 285,736 subjects. Death occurred outside health care facilities in 88% of the analyzed cases; nevertheless, autopsy was made only in 28.

[Selenium provision in heart failure of different aetiology].

Determination of selenium status of patients with chronic heart failure of various etiologies showed reduced provision of selenium compared with the control group. Statistically significant increased serum levels of selenium have occurred on average 35,9% after the correction. Intake of sea cabbage jam led to a significant increase in the level of selenium in serum only at patients with deficiency of this trace constituent.

[The topical issues of the terminology, classification, and statistics of acute forms of ischemic heart disease].

The paper discusses the problems in the formation of statistical information on acute forms of coronary heart disease (IHD) in Russia and possible ways of their solution. Among other problems, there is the detection and notification of cases of sudden coronary death as an independent nosological entity that belongs to the acute forms of IHD. The terminology and classification of the acute forms of IHD, which affect the formation of statistical data, are considered.

[Detectability of acute forms of coronary heart disease in real clinical practice].

The study was designed to evaluate the frequency of inapparent and/or unrecorded cases of acute coronary heart disease (CHD) and its influence on overall estimates of CHD mortality and morbidity. A specially developed algorithm was used to identify unrecorded cases in official medical documentation concerning 285,736 subjects. Their fraction was found to be 20.

[Administration of monoclonal antibodies to B-lymphocytes (rituximab) in rheumatoid arthritis in Russia].

Aim: To assess efficacy and tolerance to anti-B-cell drug rituximab in therapy of rheumatoid arthritis (RA) by the data of RF register of this drug.

Material And Methods: Rituximab was studied in 42 patients with high RA activity. 37 patients received rituximab according to a conventional scheme: 2 intravenous 1000 mg infusions with a 2-week interval.