Publications by authors named "S S Guldiken"
Introduction: Lymphovascular invasion is an independent prognostic marker in papillary thyroid carcinomas. In addition, integrin β4 is associated with advanced progression and metastasis in many malignancies. We aimed to investigate the relationship between integrin β4 and lymphovascular invasion in papillary thyroid carcinoma.
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- - This study aimed to identify factors affecting disease-free survival (DFS) in patients with medullary thyroid carcinoma (MTC), as previous research in this area has been limited.
- - Researchers analyzed data from 257 patients, finding that 51% had persistent/recurrent disease while 49% had no evidence of disease at follow-up, with various factors like age, metastasis, and initial response influencing DFS outcomes.
- - The key finding was that the lack of an excellent response after initial treatment is the strongest predictor of worse DFS, highlighting the need for diligent follow-up even in patients who initially respond well.
(1) Introduction: The impact of multifocality/bilaterality on the prognosis of papillary thyroid carcinoma (PTC) is a matter of debate. In order to clarify this debate, several studies have attempted to identify additional parameters associated with poor prognosis, including total tumor diameter (TTD), in the context of multifocal PTCs. In this context, this study was carried out to investigate the impact of TTD on tumor recurrence and lymph node metastasis (LNM) in PTCs.
View Article and Find Full Text PDFAims: Diabetic nephropathy is one of the major complications of Type 2 diabetes mellitus. In this study, we aimed to investigate the effects of angiotensinogen M235T/T174M and angiotensin type 1 receptor A1166C gene polymorphisms on the development of diabetic nephropathy in patients with type 2 diabetes mellitus.
Methods: This study included 100 type‑2 diabetes mellitus patients with diabetic nephropathy patients (patient group) and 99 type‑2 diabetes mellitus patients without diabetic nephropathy (control group).
SURVIVIN POSITIVITY AND PROGNOSTIC FACTORS IN PAPILLARY THYROID CARCINOMAS.
Acta Endocrinol (Buchar)
January 2021
Context: Papillary thyroid carcinoma(PTC)s are the indolent progressive tumours. Survivin is a unique bifunctional protein with cell cycle regulation and apoptosis inhibition. The expression of this protein has been shown to be increased in thyroid tumours correlated with aggressive behavior from well differentiated to anaplastic.
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