Guideline on managing thumb base osteoarthritis: The British Society for Surgery of the Hand Evidence for Surgical Treatment (BEST) findings and recommendations.

This review paper provides a summary of the evidence for non-surgical and surgical management of thumb base osteoarthritis and suggests guidelines through including and a . The guidelines were developed through systematic reviews in accordance with the British Society for Surgery of the Hand Evidence for Surgical Treatment (BEST) Process Manual, which has been accredited by the National Institute for Health and Care Excellence. A stepwise approach is recommended with initial non-invasive treatment consisting of a comprehensive and multimodal package of supported self-management.

A Simplified Protocol for Isolation and Culture of Keratinocyte Stem Cells from Neonatal Mice.

Isolation of primary keratinocyte stem cells (KSCs) from neonatal mouse epidermis is essential for studying skin physiology and related disorders. Traditional methods often struggle to balance keratinocyte proliferation and differentiation, and although recent advancements using low-calcium culture conditions have improved these techniques, protocols remain scattered. This study presents a streamlined approach to expand mouse KSCs in low-calcium medium (<0.

Simulating quantum chaos on a quantum computer.

Noisy intermediate-scale quantum (NISQ) computers provide a new experimental platform for investigating the behaviour of complex quantum systems. We show that currently available NISQ devices can be used for versatile quantum simulations of chaotic systems. We introduce a classical-quantum hybrid approach for exploring the dynamics of the chaotic quantum kicked top (QKT) on a quantum computer.

Surface energy and stress driven growth of extremely long and high-density ZnO nanowires using a thermal step-oxidation process.

Formation of highly crystalline zinc oxide (ZnO) nanowires with an extremely high aspect ratio (length = 60 μm, diameter = 50 nm) is routinely achieved by introducing an intermediate step-oxidation method during the thermal oxidation process of thin zinc (Zn) films. High-purity Zn was deposited onto clean glass substrates at room temperature using a vacuum-assisted thermal evaporation technique. Afterwards, the as-deposited Zn layers were thermally oxidized under a closed air ambient condition at different temperatures and durations.

Hybrid Polystyrene-Plasmonic Systems as High Binding Density Biosensing Platforms.

Sensitive, accurate, and early detection of biomarkers is essential for prompt response to medical decisions for saving lives. Some infectious diseases are deadly even in small quantities and require early detection for patients and public health. The scarcity of these biomarkers necessitates signal amplification before diagnosis.