Catalyst to cure: applications of a new copper-based nanocatalyst in organic synthesis and cancer treatment.

This research explores the diverse applications of copper(0) nanoparticles grafted onto boron carbon nitride nanosheets, using dill leaf extract as a natural reducing and stabilizing agent. This nanocatalyst efficiently catalyzes the synthesis of tetrazole and aniline derivatives, demonstrating good recyclability and promising potential in cancer therapy. By merging sustainability with innovation, this nanocatalyst offers transformative solutions in both synthesis and medical fields.

Outcome of Post Functional Endoscopic Sinus Surgery Nasal Irrigation with Normal Saline Versus Normal Saline with Budesonide in Patients with Sinonasal Polyposis: A Randomized Control Trial.

Chronic rhinosinusitis(CRS) is a condition characterized by inflammation of the lining of nose and sinuses lasting for 12 weeks or more. CRS with nasal polyp nasal polyp(CRSwNP) is seen in 0.5-4% of the population and is present in about 20% of patients with CRS.

Diastereoselective Synthesis of Fused Tricyclic Pyridopyrimidines via Tandem Cyclization of Allenoates and Cyclic Amidines.

The tandem cyclization of easily accessible allenoates and cyclic amidines for the synthesis of functionalized tricyclic pyridopyrimidines is reported herein. The annulation featured a broad substrate scope with good functional group tolerance under very mild conditions (35 examples, 32-85% yields). The pyridopyrimidines were obtained in a very short reaction time (1 min), at room temperature, under neat conditions, which offers an alternative way to the sustainable synthesis of functionalized pyridopyrimidines.

DBU-Catalyzed Diastereo/Regioselective Access to Highly Substituted Spiro-oxetane Oxindoles Ring Annulation of Isatins and Allenoates.

A facile and efficient method for the diastereo/regioselective synthesis of highly functionalized spiro-oxetane oxindoles has been described. The 1,8-diazabicyclo[5.4.

A Comparative Study of Antibiotic-steroid Pack with Glycerine Pack in Treatment of Acute Otitis Externa.

Objective: To compare the clinical efficacy of Antibiotic-Steroid pack with Glycerine pack for relieving pain and oedema in cases of acute otitis externa.

Study Design: A COMPARATIVE STUDY.

Setting: Tertiary care center ( S.