New subgroup 16SrXI-F phytoplasma strain associated with sugarcane grassy shoot (SCGS) disease in India.

A novel phytoplasma subgroup strain SC-Phy385 (GenBank accession number HF586648) was found associated with Sugarcane Grassy Shoot (SCGS) disease in India. Sugarcane (Saccharum officinarum L.) leaf samples with 'grassy shoot' symptoms were collected from the western region of Maharashtra state.

The ability of healthy volunteers to simulate a neurologic field defect on automated perimetry.

Objective: To determine if volunteers can simulate and reproduce 3 types of neurologic field defects: hemianopia, quadrantanopia, and central scotoma.

Design: Cross-sectional study.

Participants: Thirty healthy volunteers new to perimetry (including automated perimetry).

Withaferin A effectively targets soluble vimentin in the glaucoma filtration surgical model of fibrosis.

Withaferin A (WFA) is a natural product that binds to soluble forms of the type III intermediate filament (IF) vimentin. Currently, it is unknown under what pathophysiological contexts vimentin is druggable, as cytoskeltal vimentin-IFs are abundantly expressed. To investigate druggability of vimentin, we exploited rabbit Tenon's capsule fibroblast (RbTCF) cell cultures and the rabbit glaucoma filtration surgical (GFS) model of fibrosis.

Evaluation of extended release brimonidine intravitreal device in normotensive rabbit eyes.

Purpose: To evaluate the safety profile of a brimonidine extended release intravitreal implant, in normotensive rabbit eyes.

Methods: Devices were made from hollow poly-l-lactic acid (PLA) tubes and contained hundred micrograms of brimonidine pamoate. Device was injected intravitreally in one eye of 12 New Zealand pigmented rabbits, whereas other eye was injected with a sham implant in masked fashion.

Comparison of unenhanced and enhanced imaging protocols for angle measurements with anterior segment optical coherence tomography.

Background And Objective: To compare the intraobserver and interobserver agreement of anterior chamber angle measurements using unenhanced and enhanced imaging protocols for anterior segment optical coherence tomography (AS-OCT).

Patients And Methods: Anterior segments of 30 eyes of 15 healthy subjects (mean age: 33.8 ± 13.