Effect of zinc level and the thermal environment on the zootechnical performance and tibia-breaking strength of Japanese quails.

Japanese quails () are sensitive to zinc (Zn) deficiency, a mineral essential for growth, development, and bone health. This study evaluated the effects of different levels of Zn in the diet on zootechnical performance, organ and carcass weight, and tibial breakage resistance in quails from 1 to 42 days of age. A 5 × 2 factorial design was used, consisting of five Zn levels (30, 60, 90, 120, and 150 mg/kg) and two thermal environments (thermal comfort and heat stress), with five replicates of 10 birds per treatment.

Corrigendum: Oligodendrocyte precursor cell-derived exosomes combined with cell therapy promote clinical recovery by immunomodulation and gliosis attenuation.

[This corrects the article DOI: 10.3389/fncel.2024.

Inactivated SARS-CoV-2 induces acute skeletal muscle damage in human K18-hACE2 transgenic mice.

The pandemic due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in over 7 million global fatalities and billions of individuals diagnosed with COVID-19. Acute and chronic muscle impairment associated with SARS-CoV-2 infection affected a substantial number of patients, leading to the development of symptoms such as fatigue, muscle pain, and exercise intolerance. Our study introduces an animal model to improve understanding of the pathogenicity caused by SARS-CoV-2 in human skeletal muscle.

Phytoceutical Isoquercitrin and Ethanolic Extracts from Pequi (Caryocar coriaceum Wittm) Reverse Alcohol Withdrawal-Induced Anxiety in Adult Zebrafish (Danio rerio).

Pharmacotherapy in Alcohol Withdrawal Syndrome (AWS), which is a mental disorder, generally involves benzodiazepines due to their action via GABA, but their side effects, such as excessive sedation, mental confusion and risk of dependence, are considerable. It is important to investigate the anxiolytic potential of plants such as Caryocar coriaceum, due to the presence of secondary metabolic compounds, such as isoquercitrin, capable of promoting the reduction of anxiety during AWS. We evaluated the anxiolytic-like potential of ethanolic extracts from the leaves (EEPL) and pulp (EEPP) of C.

Ergometer for physical conditioning assessment of people with disabilities and parathletes.

Background: Wheelchair users face various health issues, such as cardiac problems, obesity, tissue deformation, and shoulder and wrist injuries. Although the subject of ergometry is known since 1912 and the mechanic of propulsion gesture and wheelchair configuration has been studied over the years, most of the equipment found in the literature are adaptations or lack the tools for standardization of techniques. This paper aims to conduct biomechanical validation of a new wheelchair ergometer (ERGO1) designed for assessing physical fitness and muscle training of the upper limbs of people with disabilities.