Efficacy of Ayurvedic treatment given to cancer patients in the prevention of COVID-19 - A Retrospective Cohort Study at Integrated Cancer Treatment and Research Centre, Wagholi.

Background: Cancer patients are considered to have a higher risk of developing severe Coronavirus Disease 2019 (COVID-19) and a higher mortality rate. Moreover, poor prognosis observed in them is associated with multiple co-morbidities. Ayurveda can prove to be effective in preventing COVID-19 as well as improving clinical outcomes against COVID-19 in cancer patients.

The role of smart electricity meter data analysis in driving sustainable development.

The analysis of Smart Electricity Meter (SEM) data, which plays an important role in sustainability of the electricity system. The widespread use SEM generates a substantial volume of data. However, when faced with an influx of new data, traditional clustering methods require re-clustering all the data from scratch.

Prediction and Characterization of Genetically Regulated Expression of Target Tissues in Asthma.

Background: Genetic control of gene expression in asthma-related tissues is not well-characterized, particularly for African-ancestry populations, limiting advancement in our understanding of the increased prevalence and severity of asthma in those populations.

Objective: To create novel transcriptome prediction models for asthma tissues (nasal epithelium and CD4+ T cells) and apply them in transcriptome-wide association study (TWAS) to discover candidate asthma genes.

Methods: We developed and validated gene expression prediction databases for unstimulated CD4+ T cells (CD4+T) and nasal epithelium using an elastic net framework.

Total Synthesis of Waltherione Alkaloids: A Strategic Molecular Diversity Approach.

We report the first total synthesis of -8-deoxoantidesmone and -waltherione M, key intermediates in the unexplored 5,6,7,8-tetrahydro-1H-quinolin-4-one waltherione (THQW) alkaloid family. These compounds have been synthesized in three steps via a diversity-oriented approach utilizing a versatile intermediate 8-bromo-5-fluoro-3-methoxy-2-methyl-1H-quinolin-4-one, which was obtained through a one-step synthesis between 2-bromo-5-fluoro-aniline and ethyl 2-methoxy-3-oxo-butanoate. This intermediate underwent a MgCl-mediated SAr reaction using alkyl Grignard reagents to provide 8-bromo-3-methoxy-2-methyl-5-alkyl-1H-quinolin-4-one.

Diagnosis of Genital Tuberculosis Unveiled by Utero-Cutaneous Fistula and Superimposed MRSA Infection: A Case Report.

Background: Both tuberculosis and Methicillin-Resistant Staphylococcus Aureus (MRSA) are known to be notorious for causing fistulas due to their characteristics of persis-tent, difficult-to-treat infections that lead to chronic inflammation, abscess formation, and tissue necrosis. There are several case reports highlighting the invasiveness and potential for fistula formation associated with both tuberculosis and MRSA infections independently, but to the best of our knowledge, this is the first case of a utero-cutaneous fistula caused by chronic infection due to MRSA, superadded on genital tuberculosis.

Case Presentation: A 35-year-old female, P3L3, visited the gynaecology outpatient depart-ment nine months after her last caesarean section with the complaint of severe pain and blood discharge from the transverse supra-pubic scar during menstruation.