Publications by authors named "S S Boiko"
Article Synopsis
- The American Academy of Dermatology (AAD) has created the Good Skin Knowledge (GSK) curriculum for children aged 8-13 to educate them about skin care and dermatologic conditions.
- A pre- and post-training survey was developed to measure the effectiveness of the GSK program in boosting participants' confidence and understanding of skin care concepts.
- Results showed a significant increase in confidence and knowledge, with at least two-thirds of participants gaining a better understanding of skin layers, the role of dermatologists, and acne causes.
Spleen tyrosine kinase (SYK) is a non-receptor cytoplasmic kinase. Due to its pivotal role in B cell receptor and Fc-receptor signalling, inhibition of SYK has been a target of interest in a variety of diseases. Herein, we report the use of structure-based drug design to discover a series of potent macrocyclic inhibitors of SYK, with excellent kinome selectivity and in vitro metabolic stability.
View Article and Find Full Text PDFDue to their high number and variety, simple sequence repeats in DNA are a valuable source of genetic markers widely used in population genetics, genetic diversity, and fingerprinting. is a cosmopolitan basidiomycete and a valuable object for biotechnology and mycology. It is often used as a model organism in genetic and population studies.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on creating co-delivery systems using paclitaxel and a prodrug of etoposide, utilizing human serum albumin (HSA) and poly(lactide-co-glycolide) nanoparticles.
- The nanoparticles were analyzed for various properties and demonstrated sizes of 90-150 nm, showing effective cytotoxicity against glioma cells, particularly Neuro2A cells.
- The results indicated a synergistic effect of the drug combinations, suggesting these delivery systems could enhance chemotherapy treatments for brain tumors, marking a novel approach using HSA-based formulations.
The fungus Schizophyllum commune is a cosmopolitan basidiomycete, which is popular as an edible, medical mushroom. It causes wood rot and often used as a model object in research. In this study, we analyzed thirty-two genomes of S.
View Article and Find Full Text PDF