Aim: To assess effects of fluvastatin monotherapy and combined therapy with aspirin and trental on hemostasis and microcirculation in atherosclerosis.
Material And Methods: Hemostasis and microcirculation were studied in 68 patients with coronary atherosclerosis and aortic atherosclerosis on fluvastatin monotherapy and on combined therapy fluvastatin + aspirin + trental.
Results: Hypolipidemic treatment with fluvastatin reduced thrombogenic blood potential due to enhancement of plasmic fibrinolytic activity [the time of XII-a dependent fibrinolysis decreased by 33% (p < 0.
Aim: To analyze lipid and non-lipid effects of 6-month administration of enduracine in patients with marked dislipoproteinemia suffering from arterial hypertension with ischemic heart disease or without it.
Materials And Methods: 40 hypertensive patients (27 males and 13 females, mean age 52.43 +/- 1.
Aim: To assess the significance of individual pain sensitivity in the development of painful and painless episodes of acute myocardial ischemia.
Materials And Methods: Bicycle ergometry test was carried out in 50 patients aged 35-65 years with angina of effort, functional classes II-III. Before bicycle ergometry, tactile and pain sensitivity thresholds and duration of pain tolerance were assessed by SSM-01 sensometer.
Corinfar-retard (CR) was tried in 146 patients, the acute test was performed in 26 cases. The findings confirm antihypertensive activity of the drug, reduced frequency of sharp changes in blood pressure and of hypertensive crises, side effects, its ability to diminish platelet aggregation. As for coronary heart disease.
View Article and Find Full Text PDF