Publications by authors named "S S Ameh"
Article Synopsis
- The study investigates the role of meningitis in child mortality under five years old, particularly focusing on data from six sub-Saharan African countries and Bangladesh.
- It employs post-mortem minimally invasive tissue sampling (MITS) to identify the causes of death and pathogens responsible for meningitis in this age group from December 2016 to December 2023.
- Findings reveal that meningitis contributed to 7% of child deaths, with common pathogens identified being Acinetobacter baumannii and Klebsiella pneumoniae, particularly affecting neonates and infants.
Article Synopsis
- The study focused on the antimicrobial susceptibility profiles of specific bacteria linked to nosocomial infections in postmortem blood from stillbirths and children under five in Sierra Leone, as part of the CHAMPS program.
- Over the study period from March 2019 to February 2022, 367 bacterial isolates were analyzed, with findings revealing that one organism was most commonly isolated, followed by two others, highlighting significant resistance patterns.
- Results indicated a high prevalence of multidrug-resistant organisms, particularly among the isolates, raising concerns about antimicrobial stewardship and the effectiveness of treatment options in the region.
Article Synopsis
- Africa has a high hypertension prevalence (46%), and schoolteachers are particularly at risk due to work and lifestyle factors, making it essential to understand these risks for better health interventions.
- A study of 427 schoolteachers in Calabar, Nigeria, found a 32% prevalence of hypertension, with significant correlations linked to age and body mass index (BMI).
- Teachers aged 30 and older, as well as those categorized as overweight or obese, faced greater odds of hypertension; therefore, health strategies should prioritize weight management for older educators.
CD4 T cells can either enhance or inhibit tumour immunity. Although regulatory T cells have long been known to impede antitumour responses, other CD4 T cells have recently been implicated in inhibiting this response. Yet, the nature and function of the latter remain unclear.
View Article and Find Full Text PDFIntroduction: Determining aetiology of severe illness can be difficult, especially in settings with limited diagnostic resources, yet critical for providing life-saving care. Our objective was to describe the accuracy of antemortem clinical diagnoses in young children in high-mortality settings, compared with results of specific postmortem diagnoses obtained from Child Health and Mortality Prevention Surveillance (CHAMPS).
Methods: We analysed data collected during 2016-2022 from seven sites in Africa and South Asia.