Identifying Factors Contributing to Dropouts in a Pilot Telenutrition Weight-Loss Program: A Qualitative Study.

Background: Telehealth programs exhibit strong potential to improve health measures and quality of life among obese and overweight individuals for whom medical nutritional therapy remains a challenge due to poor adherence and dietary compliance. Supporting weight-management programs with dietary interventions or "telenutrition" and integrating telemonitoring and/or telehealth coaching have had a significant positive impact on weight-loss patients achieving their goals in long-term interventions.

Methods: The aim of the current study was to identify the factors leading patients to drop out of a telenutrition weight-loss program, including weekly telemonitoring (total of 36 weeks) and monthly telehealth coaching (total of 6 months).

Comparing tele-pharmacy and standard clinic follow-up for newly initiated warfarin anticoagulation therapy: A retrospective study.

Objectives: To compare the effectiveness of providing telepharmacy anticoagulation to on-site clinics in achieving optimal outcomes for patients newly starting warfarin.

Methods: This single-center retrospective cohort study included adult patients who started warfarin for the first time and were monitored by clinical pharmacists either on-site or via telepharmacy anticoagulation clinics between January 2017 and March 2024. The primary outcome is to compare the time in therapeutic range (TTR) between the 2 groups.

Influence of endothelial nitric oxide synthase haplotypes on nitric oxide and peroxynitrite productions.

The impact of four clinically significant genetic variants of endothelial nitric oxide synthase (eNOS) polymorphisms on the concentrations of nitric oxide [NO] and peroxynitrite [ONOO] has been given scant consideration. This study utilized a [NO]/[ONOO] ratio to determine the extent of endothelial dysfunction caused by these variations in the eNOS gene. The single nucleotide polymorphisms (T-786C, C-665T, and Glu298Asp) and a variable number of tandem repeats (intron 4 a/b/c) were genotyped in human umbilical vein endothelial cells (HUVEC), using sanger sequencing and DNA electrophoresis, respectively.