Publications by authors named "S S Aeschbacher"

Background: There is some evidence of reduced major cardiovascular event (MACE) rates associated with moderate coffee consumption in the general population. However, there is concern about the potential risks of coffee consumption in patients with atrial fibrillation (AF). Therefore, we aimed to investigate the association between coffee consumption and MACE in AF patients.

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Since leaving Africa, human populations have gone through a series of range expansions. While the genomic signatures of these expansions are well detectable on a continental scale, the genomic consequences of small-scale expansions over shorter time spans are more challenging to disentangle. The medieval migration of the Walser people from their homeland in ssouthern Switzerland (Upper Valais) into other regions of the Alps is a good example of such a comparatively recent geographic and demographic expansion in humans.

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Background: Atrial fibrillation is an independent risk factor for the development of cognitive impairments. Regular coffee consumption has shown cognitive benefits in healthy individuals. Whether regular consumption reduces cognitive decline in vulnerable patients is controversial.

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Article Synopsis
  • The study examined the relationship between smoking habits and brain health in patients with atrial fibrillation (AF), focusing on brain lesions and volumes using MRI scans.
  • A total of 1,728 patients were analyzed, revealing that heavy smoking and longer smoking duration were linked to reduced gray matter volume and increased risk of white matter lesions (WMLs).
  • Additionally, patients who quit smoking for at least 16 years had fewer small noncortical infarcts and smaller WML volumes, indicating that long-term cessation may improve brain health.
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