Publications by authors named "S S Abdel-Aziz"

A series of 1,2,4-triazolo[1,5-]pyrimidine-based derivatives were developed and prepared by reacting chalcones - with 3-phenyl-1,2,4-triazole-5-amine (). The novel compounds were analyzed using several spectroscopic techniques, and their antimicrobial efficacies against six pathogens (Gram-negative, Gram-positive, and fungi) were tested. Most of the tested compounds exhibited significant antimicrobial activity compared to ciprofloxacin and fluconazole.

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  • The study aimed to evaluate the effectiveness of misoprostol before hysteroscopy in women who have never given birth (nulliparous).
  • A total of 13 studies involving 1,528 participants were analyzed, comparing misoprostol to various alternatives including placebo and other medications.
  • Results indicated mixed outcomes on cervical dilation and pain levels, with a significant reduction in time for cervical dilatation (p=0.03), but no strong evidence for improved ease of dilation or reduced preoperative pain.
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To study the laser acupuncture (LA) effects on postmenopausal obese women's metabolic syndrome. Randomized controlled trial. Benha university hospital.

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  • COX-2-selective drugs were pulled from the market due to heart-related side effects, leading researchers to seek new COX-2 inhibitors that also protect cardiovascular health.
  • Newly created 15 diaryl-1,2,4-triazolo[3,4-]pyrimidine hybrids showed promising results as dual COX-2 and sEH inhibitors, with some compounds demonstrating greater potency and selectivity compared to celecoxib.
  • The most effective compounds also showed strong anti-inflammatory and analgesic properties while having a positive impact on heart health, and their molecular binding was analyzed to confirm their selectivity for COX-2.
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The aim of this study is to evaluate the anti-HPV potential of a Lam seed, L. seed, and peel herbal mixture in the form of polymer film-forming systems. A clinical trial conducted in outpatient clinics showed that the most significant outcome was wart size and quantity.

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