Screening for Variants in Egyptian Patients with Pontocerebellar Malformations.

Introduction: Pontocerebellar hypoplasia (PCH) represents a group of rare disorders with prenatal onset and time-dependent loss of brain parenchyma, predominantly affecting the cerebellum and pons with variable involvement of supratentorial structures. Radiologically and pathologically, they are characterized by small cerebellum and pons. Our study aimed to screen for the gene variants in Egyptian patients with PCH for proper counseling and to describe the brain MRI and the clinical phenotype and compare, them to those described in the literature.

Origin of mysterious geothermal gas emissions in the middle of the Western Desert, stable shelf area, Dakhla Oasis, Egypt.

This work responds to what was reported in various audio-visual media channels and to queries and explanations from individuals and local residents on the causes of gaseous and thermal emissions from the Earth near the vicinity of the village of Al-Hindaw in Dakhla city, New Valley Governorate, Egypt. At the location of the fume exit area, magnetic, seismic, and electromagnetic geophysical investigations were carried out to identify the factor(s) responsible for the event in question. Rock samples were collected and studied geochemically and radiographically to assess their chemical compositions, as well as the quantity of organic chemicals that may have contributed to the burning and temperature increase.

Reactive astrocytes targeting with oral vitamin A: Efficient neuronal regeneration for Parkinson's disease treatment and reversal of associated liver fibrosis.

Introduction: A recent approach to cure neurodegenerative diseases is to reprogram fibroblasts into functioning neurons using multiple exogenous transcription factors (TFs) and micro-RNAs. Administering agents that can endogenously induce these TFs may bypass the limitations of this approach. Astrocytes may represent a part of the extrahepatic-stellate system involved in vitamin-A (V ) homeostasis.

Investigation of near-surface chemical explosions effects using seismo-acoustic and synthetic aperture radar analyses.

Chemical explosions are ground truth events that provide data, which, in turn, can enhance the understanding of wave propagation, damage assessment, and yield estimation. On 4 August 2020, Beirut, Lebanon was shocked by a catastrophic explosion, which caused devastating damage to the Mediterranean city. A second strong chemical explosion took place at the Xiangshui, China chemical plant on 21 March 2019.