Publications by authors named "S Ruotolo"
The development of cerebral cavernous malformations (CCMs) is a well-recognized sequela of irradiation to the brain in pediatric tumors, particularly in medulloblastoma, glioma, and acute lymphoblastic leukaemia. So far, only one case of cerebral cavernoma after chemotherapy with autologous hematopoietic stem cell transplantation (HSCT) has been described. We describe a case of a patient with medulloblastoma aged 18 months at the time of oncological diagnosis who was treated with high-dose chemotherapy followed by HSCT and who developed CCM two years later.
View Article and Find Full Text PDFBackground: Children with high-risk medulloblastoma are treated with chemotherapeutic protocols which may affect heart function. We aimed to assesscardiovascular events (CVE) in children with medulloblastoma/primitive neuroectodermal tumors (PNET).
Methods: We retrospectively collected data from a case series of 22 children with high-risk medulloblastoma/PNET admitted to the Santobono-Pausilipon Hospital, Naples, Italy from 2008 to 2016.
Article Synopsis
- Malignant spinal cord compression (MSCC) in children can lead to severe outcomes like paralysis and sensory loss, with limited data on its incidence and causes in kids, especially under 18.
- The study examined 44 pediatric patients admitted for MSCC since 2007, finding that most cases were due to extramedullary tumors, primarily neuroblastoma and Ewing sarcoma, often being the first symptom of new malignancies.
- Symptoms included motor deficits in all patients and pain in 60%, with a notable variation in the time between symptom onset and tumor diagnosis, particularly shorter for those with existing cancers.
Background: Diagnosis and treatment of primary lung adenocarcinoma in children remains challenging given its rarity. Here we highlight the clinical history, pathological evaluation, genomic findings, and management of a very young patient with metastatic lung adenocarcinoma.
Case Presentation: A 10-year-old white girl presented with brain metastases due to primary pulmonary adenocarcinoma.
Although dietary counseling is generally recommended in children with food allergy (FA), its effect on the nutritional status of these patients has not yet been evaluated. Our nonrandomized multicenter prospective intervention study was undertaken to investigate the effects of dietary counseling on children with FA. Anthropometric data, dietary intakes, and laboratory biomarkers of nutritional status were evaluated in children with FA (aged 6 to 36 months) before and after dietary counseling, by multidisciplinary teams composed of pediatricians, dietitians, and nurses.
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