C Fullerene Reduces the Level of Liver Damage in Chronic Alcohol Intoxication of Rats.

The liver is the main organ responsible for the metabolism of ethanol, which suffers significantly as a result of tissue damage due to oxidative stress. It is known that C fullerenes are able to efficiently capture and inactivate reactive oxygen species in in vivo and in vitro systems. Therefore, the purpose of this study is to determine whether water-soluble C fullerene reduces the level of pathological process development in the liver of rats induced by chronic alcohol intoxication for 3, 6, and 9 months, depending on the daily dose (oral administration; 0.

SPECKLE TRACKING DOBUTAMINE STRESS ECHOCARDIOGRAPHY DIAGNOSTIC ACCURACY IN PRIMARY CORONARY ARTERIES DISEASE DIAGNOSIS.

Objective: The aim of the work was to evaluate STE feasibility as DSE visualization method and its accuracy compared to coronary angiography (CAG) in the patients with moderate-tohigh coronary arteries disease (CAD) risk.

Patients And Methods: Materials and methods: We prospectively examined 140 pts (84 (60.0%) men) with suspected CAD in order to verify diagnosis and evaluate myocardial viability and coronary reserve.

Direct and indirect effects of land-use intensity on plant communities across elevation in semi-natural grasslands.

Grassland biodiversity is vulnerable to land use change. How to best manage semi-natural grasslands for maintaining biodiversity is still unclear in many cases because land-use processes may depend on environmental conditions and the indirect effects of land-use on biodiversity mediated by altered abiotic and biotic factors are rarely considered. Here we evaluate the relative importance of the direct and indirect effects of grazing intensity on plant communities along an elevational gradient on a large topographic scale in the Eastern Carpathians in Ukraine.

EFFICACY OF SPECIFIC PREVENTION OF INFLUENZA IN INDIVIDUALS WITH POLYMORPHISMS ARG753GLN OF TLR-2, LEU412PHE OF TLR-3, ASP299GLY OF TLR-4 GENES.

Objective: The aim: Is to study the efficacy of influenza vaccination for individuals with polymorphism Arg753Gln of TLR-2 gene, Leu412Phe of TLR-3 gene, and Asp299Gly of TLR-4 gene.

Patients And Methods: Materials and methods: 66 people with mutant genotypes and normal distribution of alleles of TLR-2, TLR-3, TLR-4 genes, aged 18-63, were inoculated with anti-influenza vaccine. The genotyping of Arg753Gln polymorphic site of TLR-2, Asp299Gly of TLR-4, and Leu412Phe of TLR-3 gene was carried out by polymerase chain reaction with oligonucleotide primers usage.

RADIATION PROTECTIVE ACTIVITY DURING IMPLEMENTATION OF THE STATE PROGRAM FOR THE PROTECTION OF POPULATION OF ZHOVTI VODY TOWN.

The town of Zhovti Vody is a 'capital' of uranium mining and processing industry of Ukraine. The mining and processing of uranium has been carried out in this area for more than 60 y. During this period, due to increasing production activities, the town has grown significantly.