Incidental cardiac uptake of Tc-diphosphonates is predictive of poor outcome: data from 9616 bone scintigraphies.

Background: Bone scintigraphy (BS) is highly diagnostic for amyloid transthyretin (ATTR) cardiomyopathy. Prevalence and prognostic value of BS cardiac uptake is not well established. Our aim was to assess the prevalence of subclinical cardiac ATTR amyloidosis in patients undergoing [Tc]MDP/DPD scintigraphy and to define their phenotype and prognosis.

Unravelling the intricate photophysical behavior of 3-(pyridin-2-yl)triimidazotriazine AIE and RTP polymorphs.

The development of purely organic materials showing multicolor fluorescent and phosphorescent behaviour represents a formidable challenge in view of practical applications. Herein the rich photophysical behaviour of 3-(pyridin-2-yl)triimidazotriazine () organic molecule, comprising excitation-dependent fluorescence and phosphorescence under ambient conditions in both blended films and the crystalline phase, is investigated by means of steady state, time resolved and ultrafast spectroscopies and interpreted on the basis of X-ray diffraction studies and DFT/TDDFT calculations. In particular, by proper excitation wavelength, dual fluorescence and dual phosphorescence of molecular origin can be observed together with low energy phosphorescences resulting from aggregate species.

Electric-Field-Induced Second Harmonic Generation Nonlinear Optic Response of A β-Pyrrolic-Substituted Zn Porphyrins: When Cubic Contributions Cannot Be Neglected.

In this work, we have prepared a series of A Zn porphyrins, carrying in the β-pyrrolic-position one or two π-delocalized ethynylphenyl moieties with a -NO acceptor or a -NMe donor pendant, and measured their second-order NLO response in CHCl solution at 1907 nm via the electric-field-induced second harmonic generation (EFISH) technique. For some of these compounds, we have recorded an unexpected sign and/or absolute value of μβ. Since their sterically hindered A structure should ensure the lack of significant aggregation processes in solution, we explain such anomalous EFISH results by invoking a non-negligible contribution of the electronic cubic term γ(-2ω; ω, ω, 0) to γ, as supported by a qualitative evaluation of the third-order response through the measure of the cubic hyperpolarizability (γ) and by computational evidence.

NLO-active Y-shaped ferrocene conjugated imidazole chromophores as precursors for SHG polymeric films.

New Y-shaped ferrocene conjugated imidazole chromophores were prepared and fully characterized. The Y-shaped structure was confirmed by the single crystal X-ray diffraction technique. The chromophores show interesting second-order nonlinear optical (NLO) properties in solution, as determined by the Electric-Field Induced Second Harmonic generation (EFISH) technique.

Solid State Room Temperature Dual Phosphorescence from 3-(2-Fluoropyridin-4-yl)triimidazo[1,2-:1',2'-:1″,2″-][1,3,5]triazine.

Organic room temperature persistent luminescence is a fascinating but still largely unexplored phenomenon. Cyclic-triimidazole and its halogenated (Br, I) derivatives have recently revealed as intriguing phosphors characterized by multifaceted emissive behavior including room temperature ultralong phosphorescence (RTUP) associated with the presence of H-aggregates in their crystal structure. Here, we move towards a multicomponent system by incorporating a fluoropyridinic fragment on the cyclic-triimidazole scaffold.