Publications by authors named "S Rieg"

Purpose: To analyze the longitudinal epidemiology and antimicrobial resistance (AMR) patterns of Gram-negative bloodstream infections (BSI) in Germany.

Methods: Post-hoc analysis of prospectively documented BSI due to Escherichia coli, Klebsiella spp., Enterobacter spp.

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Article Synopsis
  • Non-university hospitals in Germany provide most inpatient care, making it crucial to analyze the quality of antimicrobial prescribing in these facilities.
  • A study conducted in 2021 across 10 hospitals in Baden-Württemberg revealed that 33% of patients received antimicrobial treatment, with most prescriptions being therapeutic.
  • Findings showed low adherence to quality indicators, highlighting the need for improved prescribing practices and the implementation of effective antimicrobial stewardship programs.
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  • Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are severe, drug-induced skin conditions that can be life-threatening and are now viewed as different levels of the same disease known as epidermal necrolysis (EN).
  • A new guideline has been created based on scientific literature and expert consensus to help medical professionals in diagnosing and treating EN.
  • This guideline targets various specialists like dermatologists and intensive care doctors, as well as informing patients, families, insurers, and policymakers about EN and includes recommendations for acute care and follow-up treatment.
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  • - The study aimed to investigate the role of serotonin levels in patients experiencing post-acute sequelae of COVID-19 (PASC), a condition affecting 10-20% of those who had the virus, characterized by fatigue and other symptoms.
  • - Researchers conducted a case-control study with 34 PASC patients and 14 healthy controls, measuring serum serotonin levels using advanced testing techniques and evaluating patients' ongoing symptoms after infection.
  • - Findings revealed no significant difference in serotonin levels between PASC patients and healthy controls, indicating that serotonin is not a reliable biomarker for PASC diagnosis or treatment, specifically cautioning against using serotonin-based therapies.
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Article Synopsis
  • Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious, mostly drug-related conditions that affect the skin and mucous membranes, categorized under the umbrella term epidermal necrolysis (EN), which varies in severity.* -
  • A new guideline for diagnosing and treating SJS/TEN was created based on extensive scientific research and consensus among experts, involving various medical specialties to provide a comprehensive approach to patient care.* -
  • The guideline is designed for healthcare professionals across multiple fields, as well as patients, their families, insurers, and policymakers, with the first part specifically addressing diagnosis, initial treatment, and systemic immunotherapy.*
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