Publications by authors named "S Remadi"
Background: Benign metastasizing leiomyoma (BML) is a rare disease with an unknown etiopathogenesis that mostly affects middle-aged women with uterine leiomyoma. Many metastatic nodules outside the uterus characterize the condition. The metastases are smooth muscle lesions without malignancy.
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- Porto-sinusoidal vascular disorder (PSVD) is a liver disease characterized by vascular lesions without cirrhosis, with unknown causes in most cases, although it can be linked to coagulation issues or toxins.
- Researchers conducted genome sequencing on a Lebanese family affected by PSVD and discovered a harmful genetic variant in the FCHSD1 gene that appears to be inherited in an autosomal dominant manner.
- The variant likely increases stability of the FCHSD1 mRNA and protein, which in turn activates the mTOR pathway excessively, leading to PSVD symptoms observed in genetically edited mice.
The development of prophylactic and therapeutic agents for coronavirus disease 2019 (COVID-19) is a current global health priority. Here, we investigated the presence of cross-neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in dromedary camels that were Middle East respiratory syndrome coronavirus (MERS-CoV) seropositive but MERS-CoV free. The tested 229 dromedaries had anti-MERS-CoV camel antibodies with variable cross-reactivity patterns against SARS-CoV-2 proteins, including the S trimer and M, N, and E proteins.
View Article and Find Full Text PDFBackground: In the past decade, cervical cancer has gone from being the second to the fourth most common cancer in women worldwide, but remains the second most common in developing countries. This cancer is most commonly caused by high-risk types of human papillomavirus (HPV), mainly type 16 (HPV16), which are sexually transmitted. This study aimed to investigate the usefulness of a cyclic synthetic peptide designed from the major L1 capsid protein of HPV16 for detecting anti-HPV16 antibodies.
View Article and Find Full Text PDFBackground: Little is known about the epidemiological characteristics of papillomavirus (HPV) infection among North African countries. Herein, we conducted a molecular epidemiological study to investigate prevalence of HPV type and HPV-16 variants among cervical-screened unvaccinated Tunisian women.
Methods: Cross-sectional study was performed on 494 Tunisian women visiting Women's Healthcare Centers.