Publications by authors named "S Relph"
Article Synopsis
- This study examines the effectiveness of third-trimester ultrasound in detecting small-for-gestational age (SGA) babies, highlighting concerns about low detection rates and risks associated with false results.
- Researchers analyzed data from the DESiGN trial, focusing on stillbirth and neonatal morbidity outcomes among pregnancies classified as either false-negative, true-positive, false-positive, or true-negative for SGA.
- Findings revealed that false-negative SGA results significantly increased the risk of stillbirth compared to true-positive diagnoses, while the implications of false-positive results were also evaluated, indicating potential risks in misclassification during antenatal screening.
Objective: To identify whether maternal and pregnancy characteristics associated with stillbirth differ between preterm and term stillbirth.
Design: Secondary cohort analysis of the DESiGN RCT.
Setting: Thirteen UK maternity units.
Article Synopsis
- The study aimed to analyze if the Growth Assessment Protocol (GAP) improves the detection of large for gestational age (LGA) babies and impacts their maternal and perinatal outcomes.
- The research was conducted as a secondary analysis of a randomized trial across 11 UK maternity units, comparing the effect of GAP to standard care on pregnant women and their LGA babies born at or after 36 weeks.
- Results indicated no significant difference in LGA detection rates or maternal and perinatal outcomes between those who received GAP and those under standard care.
Objective: To identify the clinical characteristics and patterns of ultrasound use amongst pregnancies with an antenatally unidentified small-for-gestational-age (SGA) fetus, compared with those in which SGA is identified, to understand how to design interventions that improve antenatal SGA identification.
Methods: This was a prospective cohort study of singleton, non-anomalous SGA (birth weight < 10 centile) neonates born after 24 + 0 gestational weeks at 13 UK sites, recruited for the baseline period and control arm of the DESiGN trial. Pregnancy with antenatally unidentified SGA was defined if there was no scan or if the final scan showed estimated fetal weight (EFW) at the 10 centile or above.
Objective: We aimed to determine foetal losses for DCDA and MCDA twins following transabdominal CVS or amniocentesis performed <22+ weeks.
Methods: Retrospective cohort study conducted in the UK and Belgium 01/01/00-01/06/20. Cases with unknown chorionicity, monochorionic complications or complex procedures were excluded.