Systematic review of qualitative evaluations of reentry programs addressing problematic drug use and mental health disorders amongst people transitioning from prison to communities.

Background: The paper presents a systematic review and metasynthesis of findings from qualitative evaluations of community reentry programs. The programs sought to engage recently released adult prison inmates with either problematic drug use or a mental health disorder.

Methods: Seven biomedical and social science databases, Cinahl, Pubmed, Scopus, Proquest, Medline, Sociological abstracts and Web of Science and publisher database Taylor and Francis were searched in 2016 resulting in 2373 potential papers.

Assessing the impact of vulnerability on perceptions of social cohesion in the context of community resilience to disaster in the Blue Mountains.

Objective: To assess the impact of network communications, community participation and elements of vulnerability on the perception of social cohesiveness in the Blue Mountains local government area (Blue Mountains LGA).

Design: A questionnaire was administered to residents of the Blue Mountains LGA. Econometric analysis of the resulting data was undertaken.

The Impact of Observed Trauma on Parents in a PICU.

Objective: To explore parents' experiences of "observed trauma," defined as traumatic events, unrelated to their own child, that parents/carers witness while in a PICU.

Design: Exploratory qualitative study.

Setting: Nineteen-bed mixed surgical/medical PICU in a tertiary university-affiliated children's hospital.

Optimization of sphingosine-1-phosphate-1 receptor agonists: effects of acidic, basic, and zwitterionic chemotypes on pharmacokinetic and pharmacodynamic profiles.

The efficacy of the recently approved drug fingolimod (FTY720) in multiple sclerosis patients results from the action of its phosphate metabolite on sphingosine-1-phosphate S1P1 receptors, while a variety of side effects have been ascribed to its S1P3 receptor activity. Although S1P and phospho-fingolimod share the same structural elements of a zwitterionic headgroup and lipophilic tail, a variety of chemotypes have been found to show S1P1 receptor agonism. Here we describe a study of the tolerance of the S1P1 and S1P3 receptors toward bicyclic heterocycles of systematically varied shape and connectivity incorporating acidic, basic, or zwitterionic headgroups.

Community nurses' perceptions of providing bereavement care.

This study explored the perceptions of bereavement support offered to clients and their carers and family by community nurses (CNs) in three community health centres located in a single area health service. In the context of an ageing population, it is pertinent to review CNs' perceptions in providing bereavement services. Early assessment and intervention is likely to prevent complicated grief occurring in the community.