Publications by authors named "S Rattotti"

Article Synopsis
  • This study looked at treating early-stage follicular lymphoma with radiation therapy and a medicine called ofatumumab.
  • They treated patients first with radiation and then gave ofatumumab to those still having cancer traces in their blood.
  • Out of the 110 people in the study, many improved after treatment, with some showing no signs of the disease for a long time.
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Article Synopsis
  • - Marginal zone lymphomas (MZL) are a group of related subtypes that currently lack a standardized prognostic score for patients requiring systemic therapy.
  • - Researchers developed a prognostic model based on a study of 501 patients, identifying five important factors that significantly affect progression-free survival (PFS) and creating three risk categories: low, intermediate, and high.
  • - The newly proposed MZL International Prognostic Index (MZL-IPI) has been validated in multiple patient cohorts, showing reliable predictive value for both PFS and overall survival (OS) among MZL patients undergoing treatment.
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Article Synopsis
  • * Out of 12 enrolled patients, 10 responded well while 2 did not; 58.3% experienced adverse reactions, highlighting the complexities in treatment response and side effects.
  • * While the overall diversity of GM did not significantly differ between groups, there were notable differences in specific bacterial taxa, suggesting that further research is needed to explore these relationships.
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Early therapies to prevent severe COVID-19 have an unclear impact on patients with hematological malignancies. The aim of this study was to assess their efficacy in this group of high-risk patients with COVID-19 in preventing hospitalizations and reducing the SARS-CoV-2 shedding. This was a single-center, retrospective, observational study conducted in the Fondazione IRCSS Policlinico San Matteo of Pavia, Northern Italy.

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Purpose: We prospectively treated patients with hepatitis C virus (HCV)-associated indolent lymphomas with genotype-appropriate direct-acting antivirals (DAAs) with the aim to evaluate virologic and hematologic outcomes. No prospective studies in this setting have been published so far.

Methods: FIL_BArT is a prospective, multicenter, phase II trial that evaluated genotype-appropriate DAAs in untreated HCV-positive patients with indolent lymphomas without criteria for immediate conventional antilymphoma treatment.

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