Next generation legged robot locomotion: A review on control techniques.

The next generation of autonomous-legged robots will herald a new era in the fields of manufacturing, healthcare, terrain exploration, and surveillance. We can expect significant progress in a number of industries, including inspection, search and rescue, elderly care, workplace safety, and nuclear decommissioning. Advanced legged robots are built with a state-of-the-art architecture that makes use of stereo vision and inertial measurement data to navigate unfamiliar and challenging terrains.

Conservation of function without conservation of amino acid sequence in intrinsically disordered transcriptional activation domains.

Protein function is canonically believed to be more conserved than amino acid sequence, but this idea is only well supported in folded domains, where highly diverged sequences can fold into equivalent 3D structures. In contrast, intrinsically disordered protein regions (IDRs) do not fold into a stable 3D structure, thus it remains unknown when and how function is conserved for IDRs that experience rapid amino acid sequence divergence. As a model system for studying the evolution of IDRs, we examined transcriptional activation domains, the regions of transcription factors that bind to coactivator complexes.

Cardiac structural, functional and energetic assessments during and after pregnancy in women with gestational diabetes mellitus, preeclampsia and healthy pregnancy.

Background: GDM and preeclampsia are common complications of pregnancy, for which overweight/obesity is a common risk factor. Both conditions are associated with a two-to-four-fold increase in future incident heart failure, which may be linked to early maladaptive myocardial changes.

Objectives: To determine maternal myocardial structural, functional, and energetic responses to pregnancies complicated by gestational diabetes mellitus (GDM) or preeclampsia compared to healthy pregnancies (HP) at third-trimester of pregnancy and twelve-months postpartum.

Discharging the duty of candor following delayed post-endoscopy cancer diagnosis.

Endoscopic examination is not risk free. Not only are there well-known complications associated with the procedure, but malignant and pre-malignant lesions can be missed due to human factors or failures in organizational process. Duty of candor (DoC) is a legal requirement if significant harm occurs in delivery of healthcare.