Publications by authors named "S Ramel"
Article Synopsis
- The study aimed to explore and describe the sexual issues faced by females with cystic fibrosis (CF), an area that has been largely overlooked in previous research.
- The research involved adult females with CF who were currently or previously in sexual relationships, collecting data through a questionnaire and one-on-one interviews to gain deeper insights into their experiences.
- Results indicated that a significant majority (93.4%) experienced discomfort during intercourse, with common issues including lack of lubrication and pain, highlighting the need for increased awareness and better management of sexual health concerns among females with CF.
The expanded French compassionate programme for elexacaftor-tezacaftor-ivacaftor use in people with cystic fibrosis without a F508del CFTR variant: a real-world study.
Lancet Respir Med
November 2024
Background: Elexacaftor-tezacaftor-ivacaftor has been approved in Europe for people with cystic fibrosis with at least one F508del CFTR variant. Additionally, it is approved by the US Food and Drug Administration (FDA) for people with cystic fibrosis with at least one of 177 rare variants. The aims of this study were to describe the clinical response to elexacaftor-tezacaftor-ivacaftor for people with cystic fibrosis without a F508del CFTR variant in France and to determine CFTR variant responsiveness to elexacaftor-tezacaftor-ivacaftor based on the observed clinical response.
View Article and Find Full Text PDFObjective: Racism leads to disparities in health outcomes. Our objective was to determine if black race was independently associated with differences in fat accretion at discharge in a large cohort of very preterm infants (32 weeks of gestation or less).
Methods: De-identified demographic, anthropometric and body composition data were collected from seven neonatal units around the United States.
Article Synopsis
- The study investigates allergic bronchopulmonary mycoses (ABPM) in patients with cystic fibrosis, focusing on specific IgE responses to five non-Aspergillus molds.
- Researchers analyzed serum samples from 238 patients across several European countries, finding higher levels of specific IgE in these patients compared to healthy controls.
- The findings highlight the need for improved diagnostic tools for ABPM, as several cases were identified using a new scoring system, emphasizing the importance of non-A. fumigatus molds in these conditions.
Human milk improves neurodevelopment for preterm infants, but relationships between human milk and neurodevelopment for infants with critical CHD are unknown. We aimed to (1) explore associations between human milk/direct breastfeeding and neurodevelopment at 1-year and 2-year follow-up and (2) describe patterns of human milk (maternal, donor) and commercial formula during hospitalisation in the first year of life.This retrospective cohort study included infants who underwent surgery for CHD < 6 months old.
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