Publications by authors named "S Rajpurohit"
Article Synopsis
- Acute upper gastrointestinal bleeding (UGIB) has a significant mortality rate of around 10%, and while existing scoring systems exist, none effectively predict mortality outcomes.
- This study conducted in India compared the newly developed ABC score, based on age, blood tests, and comorbidities, against other pre-existing scoring systems to assess its effectiveness in predicting mortality.
- Results showed the ABC score had the highest accuracy (AUROC of 0.75) in predicting 30-day mortality, particularly showing better performance in patients with variceal bleeding compared to non-variceal bleeding.
Life-history trade-offs are an inherent feature of organismal biology that evolutionary theory posits play a key role in patterns of divergence within and between species. Efforts to quantify trade-offs are largely confined to phenotypic measurements and the identification of negative genetic-correlations among fitness-relevant traits. Here, we use time-series genomic data collected during experimental evolution in large, genetically diverse populations of to directly measure the manifestation of trade-offs in response to temporally fluctuating selection pressures on ecological timescales.
View Article and Find Full Text PDFWe conducted a study on the performance of the local hybrid exchange-correlation functional PBE0r for a set of 95 experimentally characterized iron spin-crossover (SCO) complexes [Vennelakanti, V.; 2023, 159, 024120]. The PBE0r functional is a variant of PBE0 where the exchange correction is restricted to on-site terms formulated on the basis of local orbitals.
View Article and Find Full Text PDFBeyond Bones: Exploring Primitive Neuroectodermal Tumor of Kidney.
Indian J Surg Oncol
September 2024
Article Synopsis
- Renal primitive neuroectodermal tumor (PNET) is a rare and aggressive type of cancer that typically affects bones or soft tissues but can appear in renal (kidney) tissue, particularly in young adults.* -
- This report details the case of a 28-year-old male whose renal PNET was identified after presenting with flank pain and hematuria, leading to a radical nephrectomy and chemotherapy treatment.* -
- The case emphasizes the importance of considering renal PNET in young patients with unusual kidney masses, as early intervention can significantly impact treatment outcomes and prognosis.*
Background And Aims: Assessment of the severity of substance use disorders (SUDs) in a culture-sensitive manner can help gauge the current condition of the substance user and assess change with time. The present study aimed to develop a scale for the assessment of the severity of SUDs in the Indian clinical context.
Methods: Based upon the review of literature on previously available instruments and a consultative meeting of experts, a clinician-rated scale was developed that finally comprised 41 items.