Introduction: Less biopsies were expected when large scale social restrictions were enforced during COVID-19 pandemic.
Aim: To compare the skin diseases prompting biopsy before and during the COVID-19 pandemic.
Materials And Methods: A retrospective study of skin diseases was performed; the skin problems were then grouped into major histopathological reactions.
Dermatol Online J
February 2021
Epidermolytic ichthyosis (EI, OMIM 113800) is a rare autosomal dominant keratinization disorder that is caused by keratin 1 or 10 gene mutation. It can be classified clinically based on the presence of palmoplantar hyperkeratosis involvement and extent of skin involvement. The diagnosis is made by clinical and histopathological examinations that can be confirmed by genetic testing.
View Article and Find Full Text PDFAlthough historically known as a genetic disorder, epidermodysplasia verruciformis (EV) might be acquired in patients with a noninherited defective cell-mediated immunity. This article reports a case of EV in a patient with systemic lupus erythematosus and a history of 3 years immunosuppressive methylprednisolone treatment. The microscopic features of the skin biopsy showed morphologic changes of the keratinocytes characteristic of human papilloma virus (HPV) infections and immunoreactivity to p16.
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