Publications by authors named "S Raasch"
Article Synopsis
- Aberrant levels of the transcriptional modulator ZNF423 are linked to the development of B-cell leukemia, specifically investigating its role in various acute lymphoblastic leukemia (ALL) subtypes using data from 1354 samples.
- Analysis of a pro-B ALL model using CRISPR-Cas9 showed that removing ZNF423 led to decreased cell viability and improved survival in mice, highlighting its importance in leukemia progression.
- The study uncovered a complex relationship where ZNF423 binds to EBF1 target sites, repressing gene activity and disrupting EBF1's functions, which contributes to altered transcriptional regulation and influences B-cell development and leukemogenesis.
Background: The reduction of antimicrobial usage (AMU) is in the focus in modern pig production. The objective of this study was to assess the effectiveness of alternatives to reduce AMU at herd level. In a prospective study, 68 farrow-to-finish pig herds located in Belgium, France, Germany and Sweden were recruited on a voluntary basis to implement tailor-made intervention plans to reduce their AMU.
View Article and Find Full Text PDFBackground: Antimicrobial usage in food producing animals is of major concern. A clear link between the extent of use and the development of antimicrobial resistance has already been demonstrated. To evaluate strategies that may reduce the antimicrobial usage while assuring pig health and welfare, it requires profound knowledge of factors that are associated with antimicrobial usage.
View Article and Find Full Text PDFRemission of chronic inflammatory demyelinating polyneuropathy after alemtuzumab (Campath 1H).
J Neurol Neurosurg Psychiatry
June 2006