A variational graph-partitioning approach to modeling protein liquid-liquid phase separation.

Graph neural networks (GNNs) have emerged as powerful tools for representation learning. Their efficacy depends on their having an optimal underlying graph. In many cases, the most relevant information comes from specific subgraphs.

Acute respiratory distress syndrome (ARDS): from mechanistic insights to therapeutic strategies.

Acute respiratory distress syndrome (ARDS) is a clinical syndrome of acute hypoxic respiratory failure caused by diffuse lung inflammation and edema. ARDS can be precipitated by intrapulmonary factors or extrapulmonary factors, which can lead to severe hypoxemia. Patients suffering from ARDS have high mortality rates, including a 28-day mortality rate of 34.

Transesophageal-echocardiography-guided one-stage TAVR + M-TEER credibly treated patients with severe double valve regurgitation: a case report.

Background: There are few reports about the one-stage surgery of transcatheter aortic valve replacement (TAVR) + mitral valve transcatheter edge-to-edge repair (M-TEER) around the world. TAVR + M-TEER surgery is usually performed under the simultaneous guidance of digital subtraction angiography (DSA) and echocardiography. There is no report of TAVR surgery assisted only by echocardiography all over the world.

Developing tough, fatigue-resistant and conductive hydrogels growth of metal dendrites.

Developing hydrogels with high conductivity and toughness a facile strategy is important yet challenging. Herein, we proposed a new strategy to develop conductive hydrogels by growing metal dendrites. Water-soluble Sn ions were soaked into the gel and then converted to Sn dendrites an electrochemical reaction; the excessive Sn ions were finally removed by water dialysis, accompanied by dramatic shrinkage of the gel.

Near-infrared light reflection for the early detection of proximal caries in posterior teeth: an in vivo study.

Background: The purpose of this study was to evaluate the validity of near-infrared light reflection for detecting different depths of proximal caries in posterior teeth and to compare it with commonly used clinical oral examinations and bitewing radiography images.

Methods: Twenty-six patients with a total of 516 proximal surfaces were included in this study. The ground truth of the proximal caries was determined through a consensus reached by two experienced dentists after an intraoral examination assisted by bitewing radiographs.