Publications by authors named "S R Yanamandra"
Background: Following the emergence of the JN.1 SARS-CoV-2 variant, variants with key mutations in the spike protein, such as L455F, F456L, and R346T, were identified. In early January 2024, the KP.
View Article and Find Full Text PDFBackground: In August 2023, the BA.2.86 SARS-CoV-2 variant, with over 30 spike protein mutations, emerged amidst the global dominance of XBB sub-lineages.
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- The study focused on the emergence and characterization of SARS-CoV-2 variants in Maharashtra, India, during the early second wave of COVID-19.
- A total of 189 amino-acid mutations were identified from samples, with Clade 20A being the most prevalent and a significant presence of immune-escape mutations like D614G.
- The findings highlight the importance of ongoing genomic surveillance to track the evolving variants and their potential impact on public health.
Article Synopsis
- The study investigates the seroprevalence trends of malaria, dengue, and chikungunya in a western India hospital from 2014 to 2020, highlighting co-infection challenges in diagnosis and treatment.
- The research used retrospective analysis of serum samples from suspected cases, employing various ELISA and antigen testing methods, with data analyzed using MS Excel and JMP Software.
- Findings revealed a decreasing trend in malaria cases, with a notable increase in chikungunya and dengue seropositivity, particularly among males aged 21-30, emphasizing the need for enhanced surveillance and vector control measures to manage these diseases effectively.
Background The SARS-CoV-2 Omicron variant, within two months of its detection, replaced the Delta variant to become the dominant circulating variant globally. Therefore, it is essential to understand the characteristics of the disease caused by the variant and its impact on vaccination. Methods A total of 165 confirmed Omicron cases attending a tertiary care hospital in Pune, Maharashtra, between December 2021 to February 2022 were studied.
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