Publications by authors named "S R Toms"
Background: The invasion of glioblastoma cells beyond the visible tumor margin depicted by conventional neuroimaging is believed to mediate recurrence and predict poor survival. Radiomic biomarkers that are associated with the direction and extent of tumor infiltration are, however, non-existent.
Methods: Patients from a single center with newly diagnosed glioblastoma ( = 7) underwent preoperative Q-space magnetic resonance imaging (QSI; 3T, 64 gradient directions, b = 1000 s/mm) between 2018 and 2019.
Article Synopsis
- The study investigates how social determinants of health (SDoH) like race, insurance, and income affect access to and outcomes of spine tumor surgeries, revealing disparities compared to intracranial tumor cases.
- Data from over 6 million spine tumor admissions from 2002 to 2019 were analyzed, focusing on how these SDoH correlate with surgical outcomes such as mortality, complications, and length of stay.
- Findings suggest non-White patients and those with nonprivate insurance faced lower chances of receiving surgery, worse presenting conditions, and poorer discharge outcomes, indicating significant health inequities in spine tumor treatment.
Article Synopsis
- The study investigates how neighborhood-level resource disadvantage, measured by the Area Deprivation Index (ADI), affects long-term outcomes after spine tumor surgery.
- Researchers analyzed data from 237 patients treated between 2015 and 2022, categorizing them into advantaged and disadvantaged based on their ADI scores.
- Results revealed that disadvantaged patients had worse functional status, higher ambulation deficits, and more frequent non-elective surgeries compared to their advantaged counterparts.
Introduction: Falls from cribs resulting in head injury are understudied and poorly characterized. The purpose of this study was to advance current understanding of the prevalence, descriptive characteristics of injury victims, and the types of crib fall-related head injuries (CFHI) using queried patient cases from the National Electronic Injury Surveillance System (NEISS) database.
Methods: Using the US Consumer Product Safety Commission's System NEISS database, we queried all CFHIs among children from over 100 emergency departments (EDs).
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor, known for its poor prognosis and high recurrence rate. Current standard of care includes surgical resection followed by combined radiotherapy and chemotherapy. Although immunotherapies have yielded promising results in hematological malignancies, their successful application in GBM remains limited due to a host of immunosuppressive factors unique to GBM.
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