Publications by authors named "S R Simmons"

Northern elephant seals (Mirounga angustirostris) have been integral to the development and progress of biologging technology and movement data analysis, which continue to improve our understanding of this and other species. Adult female elephant seals at Año Nuevo Reserve and other colonies along the west coast of North America were tracked annually from 2004 to 2020, resulting in a total of 653 instrument deployments. This paper outlines the compilation and curation process of these high-resolution diving and location data, now accessible in two Dryad repositories.

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As nurses experience higher work demands, finding the time and resources to complete continuing education activities can be challenging. In this innovative activity, baccalaureate nursing students offered a potential solution by developing educational posters for their clinical partners. Bridging theory and practice, this approach enhanced relationships between students and bedside nurses, promoted collaborative learning, and fostered knowledge exchange within the clinical setting.

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  • The study investigates the molecular mechanisms behind racial disparities in the outcomes and progression of schizophrenia (SCZ), highlighting the role of social stressors and their neurological effects.
  • Researchers analyzed RNA sequencing data from post-mortem brain samples of racially diverse groups to identify differing gene expressions related to race, revealing 1,514 genes with significant differences after considering other factors.
  • Findings suggest that distinct molecular pathways, especially those related to stress and immune responses, are affected by race in the context of SCZ, emphasizing the need for diverse research cohorts to understand these disparities.
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Low cerebrospinal (CSF) arginine vasopressin (AVP) concentration is a biomarker of social impairment in low-social monkeys and children with autism, suggesting that AVP administration may improve primate social functioning. However, AVP administration also increases aggression, at least in "neurotypical" animals with intact AVP signaling. Here, we tested the effects of a voluntary drug administration method in low-social male rhesus monkeys with high autistic-like trait burden.

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  • Calcification in pulmonary hypertension associated with left heart disease appears to be influenced by the interaction between RUNX2 and TAZ, which are key regulators in osteogenic processes.
  • Significant vascular calcification was observed in both patients and rat models, with elevated levels of RUNX2 and TAZ.
  • Inhibiting TAZ or RUNX2 effectively reduced vascular calcification and the progression of pulmonary hypertension in the rat model, suggesting potential therapeutic targets.
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