Optimizing costs and sustainability for gamma knife radiosurgery: A cost and breakeven analysis at India's largest neurosurgery centre.

Background: Establishing and maintaining gamma knife facility incurs significant costs, mandating healthcare institutions to meticulously assess financial implications for sustainability.

Methods: This study explores the financial implications of setting up and operating a Gamma Knife facility, with an aim to ascertain user charges for achieving breakeven. The study was conducted from January to June 2019 at the largest neurosurgery centre of an Institute of National Importance (INI), in Delhi, India.

Implementation of a Machine Learning Risk Prediction Model for Postpartum Depression in the Electronic Health Records.

This study describes the deployment process of an AI-driven clinical decision support (CDS) system to support postpartum depression (PPD) prevention, diagnosis and management. Central to this CDS is an L2-regularized logistic regression model trained on electronic health record (EHR) data at an academic medical center, and subsequently refined through a broader dataset from a consortium to ensure its generalizability and fairness. The deployment architecture leveraged Microsoft Azure to facilitate a scalable, secure, and efficient operational framework.

Insight into the removal of nanoplastics and microplastics by physical, chemical, and biological techniques.

Plastic pollutants create health crises like physical damage to tissues, upset reproductive processes, altered behaviour, oxidative stress, neurological disorders, DNA damage, gene expression, and disrupt physiological functions, as the biosphere accumulates them inadvertently through the food web. Water resources have become the generic host of plastic wastes irrespective of their particle size, resulting in widespread distribution in aquatic environments. The pre-treatment step of the traditional water treatment process can easily remove coarse-sized plastic wastes.

Large atypical parathyroid tumor - a diagnostic conundrum.

Atypical parathyroid tumor (APT) is a rare neoplasm of the parathyroid gland, which shows atypical cytological or architectural features and lacks definite diagnosis criteria for malignancy. These cases can cause diagnostic challenges owing to their rarity and similarity with thyroid neoplasm on imaging and fine needle aspiration cytology. Also, differentiating APT from giant parathyroid adenoma or parathyroid carcinoma can be challenging based on clinical, imaging or cytological features.