A Low Phase Jitter MEMS Oscillator with Centrally-Anchored Piezoelectric Resonator for Wide Temperature Range Real Time Clock Applications.

This paper describes prototype temperature compensated piezoelectric MEMS oscillators operating in the wide temperature range of -40 °C to 85 °C for RTC applications. The AlN-on-Si resonator is centrally anchored at one point and designed for low power operation with a wide frequency tuning range of 5000 ppm. The oscillators exhibit a stable sinusoidal output at about 497 kHz frequency for time keeping applications with an integrated phase jitter being 10× better than the best commercially available MEMS RTC oscillators for supplementary use in portable devices for clocking audio circuits.

ISCCM Position Statement on the Approach to and Management of Critically Ill Patients with Tuberculosis.

Unlabelled: Tuberculosis (TB) is an important cause of morbidity and mortality globally. About 3-4% of hospitalized TB patients require admission to the intensive care unit (ICU); the mortality in these patients is around 50-60%. There is limited literature on the evaluation and management of patients with TB who required ICU admission.

A survey exploring the needs, preferences, and challenges of the key stakeholders for participating in and developing pulmonary rehabilitation in Pune, India.

Considering a huge burden of chronic respiratory diseases (CRDs) in India, there is a need for locally relevant Pulmonary rehabilitation (PR) services. This cross-sectional survey was aimed to explore the interest, needs and challenges among various stakeholders for PR in Pune city, India. At the outpatient respiratory medicine department of a multi-speciality hospital in Pune, India, 403 eligible people with CRDs were invited to participate in the survey, of which 370 (92%) responded and agreed to participate.

Treatment challenges in the management of difficult-to-treat gram-positive infections: A consensus view apropos therapeutic role of novel anti-MRSA antibiotics, levonadifloxacin (IV) and alalevonadifloxacin (oral).

Purpose: Treatment of antibiotic-resistant Gram-positive infections (GPIs), including methicillin-resistant Staphylococcus aureus (MRSA) is becoming increasingly difficult, particularly in patients with multiple co-morbidities who require antibiotics with greater safety and a consistent pharmacokinetic/pharmacodynamic (PK/PD) profile. Such difficult-to-treat GPIs are often associated with poor outcomes, extended hospital stay and increased expenditure. This can be partly attributed to the limited safety and aberrant PK/PD profile of existing anti-MRSA antibiotics.