Publications by authors named "S R Palli"
Background: The function of some testis-specific genes (TSGs) in model insects have been studied, but their function in non-model insects remains largely unexplored. In the present study, we identified several TSGs in the fall armyworm (FAW), a significant agricultural pest, through comparative transcriptomic analysis. A testis-specific gene cluster (TSGC) comprising multiple functional genes and long non-coding RNAs was found.
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- Effective control of Aedes aegypti mosquitoes is vital to reduce diseases like dengue and zika, focusing on blocking their transition from larvae to adults.
- Research shows that histone deacetylases (HDACs) play a role in regulating juvenile hormone (JH) signaling and metamorphosis, particularly in other insects, but their function in Aedes aegypti is not well understood.
- Knocking down specific HDAC genes increased the expression of a key gene (Kr-h1) involved in larval development, with each HDAC affecting different biological processes in mosquito growth, leading to varied developmental issues.
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- pH-sensitive chloride channels (pHCls) are found only in invertebrates and are vital for processes like fluid regulation and food intake, with this study focusing on two specific subunits, SfpHCl1 and SfpHCl2, from the fall armyworm.
- Both subunits function similarly when expressed in frog oocytes, showing chloride selectivity with their activity impacted by changes in extracellular pH and activated by zinc ions and the insecticide emamectin benzoate.
- The study reveals significant differences in activation and deactivation properties between SfpHCl1 and SfpHCl2, highlighting their potential as targets for developing specialized insecticides.
Background: Holometabolan pupal-specifier broad-complex (BR-C) and adult specifier ecdysone-induced protein 93F (E93) are essential for metamorphosis; however, their interaction and effects on programmed cell death and cell differentiation during pupation remain unclear.
Results: Here, multiple single-guide RNA (sgRNA)-mediated mosaic knockout of BR-C induced a deformed larva/pupa intermediate phenotype in Spodoptera frugiperda. Quantitative real-time polymerase chain reaction (qPCR) analysis showed that the adult specifier E93 was prematurely expressed in the BR-C mutants during the penultimate and last instar larval stages.
Chronologically inappropriate morphogenesis () is required for maintenance of larval stages of fall armyworm.
Proc Natl Acad Sci U S A
December 2024
Broad complex (Br-C) and eip93F (E93) transcription factors promote insect metamorphosis from larva to pupa and from pupa to adult, respectively. Recently, chronologically inappropriate morphogenesis (Chinmo) has been proposed as a larval specifier in r. However, whether Chinmo is required for larval maintenance in lepidopteran insects, the underlying mechanisms involved in maintaining the larval stage, and its interactions with the JH signaling pathway are not well understood.
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