Publications by authors named "S R Niranjana"

This study emphasized on the synthesis of zinc oxide nanoparticles (ZnO NPs) in an environmentally friendly manner from the extract of Catharanthus roseus leaves and its antibacterial assessment against the pneumonia-causing pathogen Klebsiella pneumoniae. This simple and convenient phytosynthesis approach is found to be beneficial over conventional methods, wherein plants serve as excellent reducing, capping, and stabilizing agents that enables the formation of ZnO NPs without the use of harmful chemicals. The formation of ZnO NPs was confirmed through several characterization techniques such as UV-visible spectroscopy, XRD, FT-IR, SEM, HR-TEM, and EDX.

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Objectives: To assess the clinical profile of infants with late onset sepsis admitted in a tertiary care hospital in North-East India.

Methods: Prospective observational study was carried out in Department of Paediatrics, Regional Institute of Medical Sciences hospital during a period of 2 years (September 2019-August 2021).

Results: A total of 109 patients were included in the study, of which 80 were community-acquired and 29 infants were hospital-acquired cases of late onset sepsis (LOS).

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Soil salinity stress has become a serious roadblock for food production worldwide since it is one of the key factors affecting agricultural productivity. Salinity and drought are predicted to cause considerable loss of crops. To deal with this difficult situation, a variety of strategies have been developed, including plant breeding, plant genetic engineering, and a wide range of agricultural practices, including the use of plant growth-promoting rhizobacteria (PGPR) and seed biopriming techniques, to improve the plants' defenses against salinity stress, resulting in higher crop yields to meet future human food demand.

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The present study aims to establish pathogenic variability among Colletotrichum truncatum, an incitant of anthracnose disease across different chilli growing regions of Karnataka. Thirty suspected C. truncatum isolates were identified based on their morphological and conidial characteristics and further confirmed by Internal Transcribed Spacer DNA sequence analysis.

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Article Synopsis
  • The study developed a method using endophytic fungal extracts to synthesize zinc oxide nanoparticles (ZnO NPs) and assessed their antimicrobial and anticancer potential.
  • Various characterization techniques confirmed that the synthesized ZnO NPs were pure, mostly hexagonal, and ranged from 34-55 nm in size, demonstrating effective antibacterial and antifungal properties.
  • The ZnO NPs showed significant internalization in cancer cells without damaging cell morphology, exhibiting notable anticancer effects at a concentration of 1 μg/mL.
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