Publications by authors named "S R Mallery"

Article Synopsis
  • Researchers previously found that benzo[a]pyrene (B[a]P), a carcinogen in tobacco smoke, caused significantly more DNA damage in smokers' buccal cells compared to non-smokers, indicating a link to oral squamous cell carcinoma (OSCC).
  • A Phase 0 clinical study involving 27 smokers tested the effects of black raspberry (BRB) lozenges on reducing B[a]P-induced DNA damage over an 8-week period.
  • Results showed a significant reduction in DNA damage at various points during and after BRB administration, suggesting its potential as a chemopreventive agent against tobacco-related OSCC.
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Background: Calcifying odontogenic cysts (Gorlin cysts) most commonly present centrally and have only rarely been reported in peripheral locations. The purpose of this report is to describe a new case of peripheral calcifying odontogenic cyst (PCOC) occurring in the anterior maxillary gingiva and to review the management and differential diagnosis of such a lesion.

Methods: A 37-year-old female presented with a long-standing submucosal nodule on the gingiva between the maxillary central incisors, with asymptomatic growth over the last three years.

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Article Synopsis
  • Hospitalized patients with acute necrotizing pancreatitis (ANP) are at risk for venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), often going unnoticed.
  • A study of 643 ANP patients revealed a 12.5% occurrence of VTE, typically developing around 16 days post-diagnosis.
  • Key risk factors for VTE identified were age over 60, extensive necrosis around the pancreas, infected necrosis, and lengthy hospital stays of 14 days or more, suggesting the need for better screening and prevention strategies in high-risk patients.
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True malignant mixed tumors, also known as salivary gland carcinosarcoma (SCS), are uncommon yet highly aggressive lesions associated with a poor prognosis. These tumors exhibit a distinctive biphasic structure characterized by both epithelial and mesenchymal components. Recent research has shown that the majority of SCS cases stem from pre-existing pleomorphic adenomas (PAs), suggesting a stepwise developmental pattern.

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