Publications by authors named "S R Lentz"
Anticoagulation Among Patients Hospitalized for COVID-19 : A Systematic Review and Prospective Meta-analysis.
Ann Intern Med
December 2024
Background: Reported results of clinical trials assessing higher-dose anticoagulation in patients hospitalized for COVID-19 have been inconsistent.
Purpose: To estimate the association of higher- versus lower-dose anticoagulation with clinical outcomes.
Data Sources: Randomized trials were identified from the World Health Organization's International Clinical Trials Registry Platform and ClinicalTrials.
Purpose: To determine if dual-degree training [ie, completion of a National Institutes of Health (NIH)-funded MD/PhD program], among other professional development and demographic variables, predicted academic productivity (eg, K-to-R conversion, number of publications, etc.) among early-career surgeon-scientists.
Methods: We analyzed publicly available data from the National MD/PhD Program Outcomes Study and the Association of American Medical Colleges Graduate Medical Education Track database to identify trends in the number and proportion of MD/PhD graduates pursuing surgical specialties.
Article Synopsis
- The use of non-pharmaceutical interventions (NPIs) during COVID-19 led to a decrease in various respiratory illnesses but created a build-up of susceptible individuals for future outbreaks.
- Unlike other respiratory pathogens that rebounded quickly after NPIs, Mycoplasma pneumoniae (Mp) outbreaks have been significantly delayed, with reports of delays over three years in Europe and Asia.
- Researchers are employing mathematical models to forecast a significant Mp outbreak in the US, highlighting the impact of NPIs and decreasing immunity on the duration of epidemic delays.
Article Synopsis
- This study tested pegcetacoplan, a targeted therapy aimed at treating these conditions, over 48 weeks in two patient groups with CAD and wAIHA who received either 270 or 360 mg/day.
- Results showed that pegcetacoplan was generally well tolerated with minimal serious side effects, and it effectively increased hemoglobin levels and reduced hemolysis in both groups.