Use of saphenous vein to reimplant intercostal arteries during thoraco-abdominal aortic replacement.

Spinal cord ischemia (SCI) is a major debilitating complication of thoraco-abdominal aortic aneurysm (TAAA) repair, even in experienced centers. Several strategies are employed to reduce the incidence of SCI and the resultant paraplegia, yet the optimum method is unknown. We describe our experience of using the reversed saphenous vein graft (RSVG) as a conduit to reimplant the intercostal arteries (ICAs).

Diverse priming outcomes under conditions of very rare precursor B cells.

Rare B cells can have special pathogen-recognition features giving them the potential to make outsized contributions to protective immunity. However, rare naive B cells infrequently participate in immune responses. We investigated how germline-targeting vaccine antigen delivery and adjuvant selection affect priming of exceptionally rare BG18-like HIV broadly neutralizing antibody-precursor B cells (~1 in 50 million) in non-human primates.

Dose-dependent regulation of immune memory responses against HIV by saponin monophosphoryl lipid A nanoparticle adjuvant.

The induction of durable protective immune responses is the main goal of prophylactic vaccines, and adjuvants play an important role as drivers of such responses. Despite advances in vaccine strategies, a safe and effective HIV vaccine remains a significant challenge. The use of an appropriate adjuvant is crucial to the success of HIV vaccines.

Use of smartphone sensor data in detecting and predicting depression and anxiety in young people (12-25 years): A scoping review.

Digital phenotyping is a promising method for advancing scalable detection and prediction methods in mental health research and practice. However, little is known about how digital phenotyping data are used to make inferences about youth mental health. We conducted a scoping review of 35 studies to better understand how passive sensing (e.

Lay Health Worker Interventions in Rheumatology: A Scoping Review.

Objective: To determine next steps for lay health worker (LHW) intervention research, specifically in patients with rheumatic musculoskeletal diseases (RMDs), there is a need to establish what strategies have been effective for chronic disease management thus far. The goal of this scoping review is to collate the literature of LHW interventions for adults with RMDs to inform next steps for LHW research.

Methods: A comprehensive literature search was performed in the following databases from inception to September 2021: Ovid Medline, Ovid Embase, CINAHL, PsycINFO, and The Cochrane Library.