Publications by authors named "S R Haile"
The advent of long-read (LR) sequencing technologies has provided a direct opportunity to determine the structure of transcripts with potential for end-to-end sequencing of full-length RNAs. LR methods that have been described to date include commercial offerings from Oxford Nanopore Technologies (ONT) and Pacific Biosciences. These kits are based on selection of polyadenylated (polyA+) RNAs and/or oligo-dT priming of reverse transcription.
View Article and Find Full Text PDFHelicobacter infection is a key cause of gastric B cell mucosa-associated lymphoid tissue (MALT) lymphoma. This study examined the role of B cell-activating factor (BAFF), a major driver of B cell proliferation and many B cell disorders, in this malignancy using a model in which conditional knockout mice for NOD-like receptor family CARD domain-containing 5 (Nlrc5) are infected with Helicobacter felis. Gastric BAFF production was significantly increased in H.
View Article and Find Full Text PDFBackground: The diagnosis of leptomeningeal metastatic disease has major prognostic and therapeutic implications. We report 13 patients with a radiologically distinct kind of focal, enhancing leptomeningeal lesion on brain MRI that mimics leptomeningeal metastatic disease.
Methods: These patients were assessed at University Health Network (Toronto, Canada) between January 2001 and December 2023.
Article Synopsis
- A study was conducted to evaluate the health-related quality of life (HRQOL) of very preterm children (born before 32 weeks) compared to their full-term siblings and the general population, involving 442 preterm children and 145 of their siblings.
- It found that very preterm children showed similar HRQOL scores to full-term siblings and peers, suggesting preterm birth does not significantly impair HRQOL.
- Chronic health conditions, age, and respiratory issues were identified as significant factors affecting HRQOL in preterm children, indicating potential areas for improvement.
Importance: Infections and complications following cesarean delivery are a significant source of maternal mortality in Ethiopia.
Objective: To study the effectiveness of a program to strengthen compliance with perioperative standards and reduce postoperative complications following cesarean delivery.
Design, Setting, And Participants: This stepped-wedge cluster randomized clinical trial included patients undergoing cesarean delivery from August 24, 2021, to January 31, 2023, at 9 hospitals organized into 5 clusters in Ethiopia.