Age at menarche and risk of premature coronary artery disease: results from Iran premature coronary disease (IPAD) study.

Background: Premature coronary artery diseases (PCAD) is a major health concern. Finding the potential risk factors for this health issue is crucial for early detection and prevention. This study aimed to evaluate the relation between age at menarche and PCAD presence and severity.

Dietary patterns and premature coronary artery disease: result from the Iran premature coronary artery disease (IPAD) study.

Background: Premature coronary artery disease (PCAD) is one of the major health concerns leading to considerable death and disabilities. This study aimed to evaluate the relationship of dietary patterns with risk of PCAD.

Methods: Iran premature coronary diseases (IPAD) is a case-control study consists of 3159 participants.

A Simple and Cost-Efficient Method for the Production of Recombinant Horseradish Peroxidase in E. coli.

Horseradish peroxidase (HRP) is a chromogenic glycoenzyme widely used in research, diagnostics, and therapeutics. Due to its high demand, various eukaryotic and prokaryotic expression systems have been employed for the production of recombinant HRP. Eukaryotic systems yield properly folded, fully functional enzymes with the necessary post-translational modifications.

Ability of a novel primer to enhance the polymerization of a self-cured resin composite.

Objective: This study evaluated the degree of conversion (DC), polymerization kinetics, and temperature of a new self-cure bulk-fill resin-based composite (Stela Automix, SDI).

Methods: The study was divided into seven groups: (1) Stela Primer, (2) Stela Automix, (3) Stela Automix exposed to light for 20 s after 100 s, (4) Stela Primer with Stela Automix, (5) Stela Primer with Stela Automix and exposed to light for 20 s after 100 s, (6) Scotchbond Universal with Stela Automix, and (7) Scotchbond Universal with Stela Automix and exposed to light for 20 s after 100 s. The real-time reaction rates and DC at the bottom of 2 mm thick specimens at ∼32 °C were measured at 720 s after insertion using a spectrometer with an Attenuated Total Reflectance detector.

Superior Anti-arrhythmogenic Effect of Combined Conditioning with Nicotinamide Mononucleotide and Ubiquinol in Myocardial Ischemia/Reperfusion Injury in Aged Rats.

Purpose: Lethal ventricular arrhythmias are a significant clinical concern following reperfusion therapies in elderly patients with myocardial infarction. The combination of multi-target therapies to achieve optimal anti-arrhythmogenesis and improve the chances of successful translation for patient benefit has prompted considerable interest. This study examined the anti-arrhythmic effect of nicotinamide mononucleotide (NMN)/ubiquinol combination treatment following myocardial ischemia/reperfusion (IR) injury in aged rats, with an emphasis on the role of oxidative stress and nitric oxide (NO).