Glutathione Peroxidase (GPx) and Superoxide Dismutase (SOD) in Oropharyngeal Cancer Associated with EBV and HPV Coinfection.

Recent reports have pointed to the link between persistent inflammation, oxidative stress, and carcinogenesis; however most of the studies concerning the role of viruses in head and neck cancer (HNC) are focused mainly on one type of virus. Our present study aimed to study the relationship between Epstein-Barr virus/human papilloma virus (EBV/HPV) coinfection and glutathione peroxidase (GPx) and superoxide dismutase (SOD) level in oropharyngeal cancer. Fresh-frozen tumor tissue samples were collected from 128 patients with oropharyngeal cancer infected with EBV or HPV or with EBV/HPV coinfection.

Serum EBV antibodies and LMP-1 in Polish patients with oropharyngeal and laryngeal cancer.

Background: The association between Epstein-Barr virus (EBV) and the development of head and neck cancer was reported by many researchers. The aim of the present study was to detect EBV DNA and EBV antibodies in 110 Polish patients with oropharyngeal and laryngeal cancer compared to 40 healthy individuals.

Methods: Frozen tumor tissue fragments were tested using nested PCR assay for EBV DNA detection.

Synergetic combination of different types of defect to optimize pinning landscape using BaZrO(3)-doped YBa(2)Cu(3)O(7).

Retaining a dissipation-free state while carrying large electrical currents is a challenge that needs to be solved to enable commercial applications of high-temperature superconductivity. Here, we show that the controlled combination of two effective pinning centres (randomly distributed nanoparticles and self-assembled columnar defects) is possible and effective. By simply changing the temperature or growth rate during pulsed-laser deposition of BaZrO(3)-doped YBa(2)Cu(3)O(7) films, we can vary the ratio of these defects, tuning the field and angular critical-current (Ic) performance to maximize Ic.

Smectic vortex phase in optimally doped YBa2Cu3O7 thin films.

Angular dependent resistivity measurements of optimally doped YBa2Cu3O7 films in fields H pulsed to 50 T are presented. Up to the highest H, the vortex melting field Hm increases and vortex motion is reduced for H aligned with the correlated pinning centers along the main crystalline axes, otherwise 3D anisotropic scaling describes the vortex dynamics. For H parallel ab, the rapid increase in Hm at low temperatures and a critical exponent analysis near Hm confirm the presence of the liquid-crystalline smectic phase predicted for layered superconductors.

Materials science challenges for high-temperature superconducting wire.

Twenty years ago in a series of amazing discoveries it was found that a large family of ceramic cuprate materials exhibited superconductivity at temperatures above, and in some cases well above, that of liquid nitrogen. Imaginations were energized by the thought of applications for zero-resistance conductors cooled with an inexpensive and readily available cryogen. Early optimism, however, was soon tempered by the hard realities of these new materials: brittle ceramics are not easily formed into long flexible conductors; high current levels require near-perfect crystallinity; and--the downside of high transition temperature--performance drops rapidly in a magnetic field.