Publications by authors named "S R Dbar"
Aim: To compare the effect of a diet low in fermentable oligo-, di-, monosaccharides and polyols (fermentable oligosaccharides, disaccharides, monosaccharides and polyols - FODMAP) and rebamipide on carbohydrate tolerance and disaccharidases activity in patients with maldigestive enteropathy (ENMP).
Materials And Methods: The study included 61 patients with ENMP with reduced small intestine carbohydrases. Their glucoamylase activity was 100 ng glucose/mg tissue × min (quartile 53, 72), maltase - 504 (quartile 258, 708), sucrase - 43 (quartile 25, 58), lactase - 8 (quartile 4, 20).
Background: Irritable bowel syndrome (IBS) is a biopsychosocial model based on the malfunction of "brain-intestinal linking".
Aim: To improve diagnostics of the severe IBS accompanied with somatoform disorders by using balloon dilatation test (BDT) and optimize the therapy by using antidepressants from the serotonin and noradrenaline reuptake inhibitor type.
Materials And Methods: 61 patients with severe IBS and diarrhea were examined, among them 29 female with a median age of 31 years old (24; 36), and 31 male with a median age of 31 (24; 36) years old.
Celiac crisis (CC) is a rare life-threatening course of celiac disease, observed mainly in children. In adults, CK can be the first manifestation of the disease and, very rarely, a relapse that occurs in patients who do not follow the gluten-free diet (AGD). Triggers can be stress, surgery, childbirth, etc.
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- FBD may be linked to reduced enzyme activity, particularly disaccharidases, which could improve diagnosis and treatment if identified early.
- A study of 82 FBD patients found high rates of deficiencies in lactase (86.5%), maltase (48.7%), sucrase (50%), and glucoamylase (84.1%), with many showing reduced overall enzyme activity.
- Results indicated that 95.2% of patients had low enzyme function related to carbohydrate digestion, suggesting a strong connection between disaccharidase deficiency and gastrointestinal symptoms in FBD.
Article Synopsis
- SARS-CoV-2 enters the body primarily through the ACE-2 receptor, which is most concentrated in the lungs but also present in the small intestine.
- The virus can cause intestinal symptoms at various stages of the disease due to its interaction with enterocytes in the gut.
- The review covers how the virus spreads via the fecal-oral route, along with diagnosis and treatment options for COVID-19 that involve intestinal issues.