How community connection, homophobia, and racism shape gene expression in sexual minority men with and without HIV.

Objective: Although sexual minority men experience substantial discrimination, in addition to increased risk for several serious mental and somatic health problems, the biological mechanisms underlying these effects are unclear. To address this issue, we examined how experiences of social safety (i.e.

The Friend Who Helps You Move, but Is Really Only There for the Free Beer and Pizza: An Update on Antimicrobial Susceptibility Testing (AST) and Breakpoints for Companion Animal Dermatology.

Antimicrobial resistance is a significant public health threat and a major challenge for treatment of companion animal skin infections. Antimicrobial susceptibility testing (AST) is a critical tool which clinicians should employ when a patient may need antimicrobials beyond those deemed "first-tier." Clinicians may have noted that many more isolates of Staphylococcus sp.

RNA encodes physical information.

Most amino acids are encoded by multiple codons, making the genetic code degenerate. Synonymous mutations affect protein translation and folding, but their impact on RNA itself is often neglected. We developed a genetic algorithm that introduces synonymous mutations to control the diversity of structures sampled by an mRNA.

A model of occupational stress to assess impact of COVID-19 on critical care and redeployed nurses: a mixed-methods study.

Objective: To use the job demands-resources model of occupational stress to quantify and explain the impact of working in critical care during the COVID-19 pandemic on nurses and their employing organisation.

Design: Two-phase mixed methods: a cross-sectional survey (January 2021-March 2022), with comparator baseline data from April to October 2018 (critical care nurses only), and semistructured interviews.

Participants: Critical care nurses ( = 461) and nurses redeployed to critical care ( = 200) who worked in the United Kingdom National Health Service (primarily Scotland) between January 2021 and March 2022.