A conceptual framework to assess the health, socioeconomic and environmental burden of chronic kidney disease.

Chronic kidney disease (CKD) is a global health challenge that affects patients, caregivers, healthcare systems, the environment and national economies. Despite its far-reaching impact, there is no framework to systematically evaluate national CKD prevention and management programmes or evaluate the societal burden of disease. This paper has two objectives: first, to introduce a comprehensive framework to assess national programmes, which recognises gaps and weaknesses and identifies feasible policy interventions to reduce overall CKD burden; second, to present some key challenges and success stories in delivering CKD services delivered in eight different country settings.

Deep Learning-Based Three-Dimensional Analysis Reveals Distinct Patterns of Condylar Remodelling After Orthognathic Surgery in Skeletal Class III Patients.

Objective: This retrospective study aimed to evaluate morphometric changes in mandibular condyles of patients with skeletal Class III malocclusion following two-jaw orthognathic surgery planned using virtual surgical planning (VSP) and analysed with automated three-dimensional (3D) image analysis based on deep-learning techniques.

Materials And Methods: Pre-operative (T1) and 12-18 months post-operative (T2) Cone-Beam Computed Tomography (CBCT) scans of 17 patients (mean age: 24.8 ± 3.

Is fossil fuel combustion still a major contributor to atmospheric aerosol carbonaceous fractions in the Po Valley? Results from a C-based source apportionment.

C measurements on the carbonaceous fractions of atmospheric aerosol are an important tool for source apportionment. In this paper, a C-based source apportionment study was carried out on samples collected during winter 2021 at an urban background site in the Po Valley, one of the main pollution hot-spot areas in Europe. The samples were prepared using MISSMARPLE (MIlan Small-SaMple Automated Radiocarbon Preparation LinE for atmospheric aerosol), a recently developed sample preparation line for C measurements on atmospheric aerosol carbon fractions, specifically targeting small samples (about 50 μgC).

Impact of FESS on symptomatology and quality of life of patients with CRSsNP.

Purpose: Chronic rhinosinusitis (CRS) has an impact on health related quality of life (HRQOL). The objective of this study was to examine generic and disease specific HRQOL and symptoms in CRS patients before and 6 months after sinus surgery.

Methods: This prospective, observational study consisted of 30 patients with chronic sinusitis.

Projecting the Population Level Burden of CKD Progression According to Urine Albumin-to-Creatinine Ratio Categories.

Introduction: Urinary albumin-to-creatinine ratio (uACR) is an independent predictor of chronic kidney disease (CKD) progression. However there is limited evidence on the burden of CKD according to uACR categories at the population level. This study estimates future clinical and financial burden of CKD according to uACR categories using the Inside CKD microsimulation.