Inflammation mediates the association between muscle mass and accelerated phenotypic aging: results from the NHANES 2011-2018.

Background: Muscle mass plays a pivotal role in health maintenance, yet its connection to biological aging remains underexplored. This study investigates the association between appendicular skeletal muscle mass index (ASMI) and phenotypic age(PhenoAge), while examining the mediating role of systemic inflammation.

Methods: The analysis included 7,440 participants from the NHANES 2011-2018.

Homochiral layered indium phosphonates: solvent modulation of morphology and chiral discrimination adsorption.

Assembling chiral coordination polymers into nano/microflower structures may improve their performance in applications such as chiral recognition and separation. In this study, we chose a chiral metal phosphonate system, , In(NO)/-, -pempH [pempH = (1-phenylethylamino)methylphosphonic acid], and carried out systematic work on the self-assembly of this system in different alcohol/HO mixed solvents under solvothermal conditions. Enantiomeric compounds -, -[In(pempH)(μ-OH)(HO)](NO) (R-, S-1) were obtained showing dense layered structures, but their morphologies varied with alcohol solvent.

Deep learning-based free-water correction for single-shell diffusion MRI.

Free-water elimination (FWE) modeling in diffusion magnetic resonance imaging (dMRI) is crucial for accurate estimation of diffusion properties by mitigating the partial volume effects caused by free water, particularly at the interface between white matter and cerebrospinal fluid. The presence of free water partial volume effects leads to biases in estimating diffusion properties. Additionally, the existing mathematical FWE model is a two-compartment model, which can be well posed for multi-shell data.

Identification and characterization of the Cul t 1 as major allergen from biting midge Culicoides tainanus.

Background: Midges are widely distributed globally. They can transmit numerous serious diseases as well as trigger an allergic reaction in the host. Their saliva contains a variety of proteins that act as sensitizers to stimulate the host's immune response, leading to IgE-mediated allergic symptoms.

A Modified Ligature-Induced Peri-Implantitis Murine Model and RNA Sequencing Analysis Compared With Human Subjects.

Aim: To propose a modified method for establishing a peri-implantitis murine model, assess the gene expression profile and immune cell infiltration of the gingiva and alveolar bone, and evaluate the transcriptomic similarity between patients with peri-implantitis and the corresponding murine model.

Materials And Methods: A ligature-induced peri-implantitis murine model was established using an immediate implant placement approach. RNA sequencing was performed to determine the transcriptomic profiles of peri-implant tissues from mice, patients with peri-implantitis and healthy individuals.